dc.contributor.author | DEVINE, KEVIN | en |
dc.date.accessioned | 2012-01-13T16:14:50Z | |
dc.date.available | 2012-01-13T16:14:50Z | |
dc.date.issued | 2012 | en |
dc.date.submitted | 2012 | en |
dc.identifier.citation | Kevin M. Devine, Bacterial L-forms on tap: an improved methodology to generate Bacillus subtilis L-forms heralds a new era of research, Molecular Microbiology, 83, 1, 2012, 10 13 | en |
dc.identifier.other | Y | en |
dc.identifier.uri | http://hdl.handle.net/2262/61671 | |
dc.description | PUBLISHED | en |
dc.description.abstract | Bacterial L-forms are cell wall-less forms of bacteria that usually grow with a conventional cell wall. Despite being important for research, L-forms are difficult to generate reproducibly and research in this area is challenging. The manuscript published in this issue by Dominguez-Cuevas and colleagues reports a method to rapidly, quantitatively and reproducibly generate populations of L-forms in Bacillus subtilis. Importantly, the methodology may be applicable to other bacteria heralding a new era of L-form research. Moreover, the genetic requirements of this method provide insights into how Lipid II synthesis and autolysin expression/activity are normally balanced and the central role of the WalRK two-component system in this process. | en |
dc.format.extent | 10-13 | en |
dc.language.iso | en | en |
dc.relation.ispartofseries | Molecular Microbiology | en |
dc.relation.ispartofseries | 83 | en |
dc.relation.ispartofseries | 1 | en |
dc.rights | Y | en |
dc.subject | Immunology | en |
dc.subject | Infection | en |
dc.subject | Bacillus subtilis | en |
dc.title | Bacterial L-forms on tap: an improved methodology to generate Bacillus subtilis L-forms heralds a new era of research | en |
dc.type | Journal Article | en |
dc.contributor.sponsor | Science Foundation Ireland (SFI) | en |
dc.type.supercollection | scholarly_publications | en |
dc.type.supercollection | refereed_publications | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/kdevine | en |
dc.identifier.rssinternalid | 76127 | en |
dc.subject.TCDTheme | Immunology, Inflammation & Infection | en |
dc.identifier.rssuri | http://dx.doi.org/10.1111/j.1365-2958.2011.07922.x | en |