De Novo Origins of Human Genes
Citation:
Daniele Guerzoni, Aoife McLysaght, De Novo Origins of Human Genes, PLoS Genetics, 7, 11, e1002381, 2011Download Item:
Abstract:
Where do new genes come from? For a long time the answer to that question has simply been ?from other genes?. The most prolific source of new loci in eukaryotic genomes is gene duplication in all its guises: exon shuffling, tandem duplication, retrocopying, segmental duplication, and genome duplication. However, in recent years there has been a growing appreciation of the oft-dismissed possibility of evolution of new genes from scratch (i.e., de novo) as a rare but consistent feature of eukaryotic genomes
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http://people.tcd.ie/mclysagaDescription:
PUBLISHED
Author: Mc Lysaght, Aoife
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Journal ArticleCollections
Series/Report no:
PLoS Genetics7
11, e1002381
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Full text availableKeywords:
Genetics, Gene duplicationSubject (TCD):
Genes & SocietyMetadata
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