A concise synthesis of asymmetrical N,N'-disubstituted guanidines
Citation:
Daniel H. O'Donovan and Isabel Rozas, A concise synthesis of asymmetrical N,N'-disubstituted guanidines , Tetrahedron Letters, 52, 32, 2011, 4117-4119Download Item:
A concise synthesis of asymmetrical N,N?-disubstituted guanidines.pdf (Published (author's copy) - Peer Reviewed) 241.3Kb
Abstract:
We present a new and concise method for the preparation of asymmetrical N,N?-disubstituted guanidines starting from thiourea via the reaction of N-Boc-protected N?-alkyl/aryl substituted thioureas with an amine in the presence of mercury(II) chloride and triethylamine.
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Irish Research Council for Science and Engineering Technology (IRCSET)
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http://people.tcd.ie/rozasiDescription:
PUBLISHED
Author: O'DONOVAN, DANIEL; ROZAS, ISABEL
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Journal ArticleCollections:
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Tetrahedron Letters52
32
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Full text availableKeywords:
Organic chemistry, Guanidine, Thiourea, One-pot synthesisSubject (TCD):
Nanoscience & MaterialsLicences: