The enantioselective benzoin condensation promoted by chiral triazolium precatalysts: stereochemical control via hydrogen bonding.
Citation:
S. E. O Toole and S. J. Connon, The enantioselective benzoin condensation promoted by chiral triazolium precatalysts: stereochemical control via hydrogen bonding., Organic Biomolecular Chemistry, 7, 17, 2009, 3584-3593Download Item:
Abstract:
The design of a new class of triazolium ion precatalysts incorporating protic substituents is described.
These materials promote the enantioselective benzoin condensation of a range of aromatic aldehydes
(1?62% ee). Catalyst evaluation studies strongly support the involvement of hydrogen bond donation by
the catalyst in the stereocentre-forming step of the catalytic cycle.
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Grant Number
Science Foundation Ireland (SFI)
Author's Homepage:
http://people.tcd.ie/connonsDescription:
PUBLISHEDPMID: 19675916
Author: CONNON, STEPHEN
Type of material:
Journal ArticleCollections
Series/Report no:
Organic Biomolecular Chemistry7
17
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Full text availableKeywords:
Organic chemistry, hydrogen bondingSubject (TCD):
Nanoscience & MaterialsMetadata
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