Browsing Pharmacology & Therapeutics by Author "BENNETT, KATHLEEN"
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Antimicrobial management and appropriateness of treatment of urinary tract infection in general practice in Ireland.
BENNETT, KATHLEEN (2011)BACKGROUND: Urinary tract infections (UTIs) are the second most common bacterial infections in general practice and a frequent indication for prescription of antimicrobials. Increasing concern about the association between ... -
A cohort study of metformin exposure and survival in patients with stage I-III colorectal cancer
BENNETT, KATHLEEN (2013)Background: Preclinical evidence suggests a beneficial effect of metformin in colorectal cancer. This study aimed to investigate associations between metformin exposure and colorectal cancer–specific survival using ... -
Comparing primary prevention with secondary prevention to explain decreasing coronary heart disease death rates in Ireland 1985 - 2000
BENNETT, KATHLEEN (2007)BACKGROUND: To investigate whether primary prevention might be more favourable than secondary prevention (risk factor reduction in patients with coronary heart disease(CHD)). METHODS: The cell-based IMPACT CHD mortality ... -
A competing risks prescription refill model of compliance and persistence.
BENNETT, KATHLEEN (2010)Objectives There is evidence to suggest that noncompliant and nonpersistent behaviors have differing risk factors, clinical consequences, and responses to intervention. This has led to calls for these behaviors to be defined ... -
Modelling Coronary Heart Disease Mortality declines in the Republic of Ireland, 1985-2006
BENNETT, KATHLEEN (2013)BACKGROUND: Consistent declines in coronary heart disease (CHD) death rates have been previously observed in Ireland since 1985. AIMS & METHODS: To use the previously validated Irish IMPACT CHD mortality model to ... -
A nested case-control study of adjuvant hormonal therapy persistence and compliance, and early breast cancer recurrence in women with stage I-III breast cancer
BENNETT, KATHLEEN (2013)Background: Non-persistence and non-compliance are common in women prescribed hormonal therapy for breast cancer, but little is known about their influence on recurrence. Methods: A nested case–control study of ... -
Prescribing patterns of glucosamine in an older population: a national cohort study
BENNETT, KATHLEEN (2013)Background Glucosamine is commonly prescribed as a disease modulating agent in osteoarthritis. However, the evidence to date suggests that it has a limited impact on the clinical symptoms of the disease including joint ... -
The prevalence and ingredient cost of chronic comorbidity in the Irish elderly population with medication treated type 2 diabetes: A retrospective cross-sectional study using a national pharmacy claims database.
BENNETT, KATHLEEN; TEELING, MARY (2013)Background Comorbidity in patients with diabetes is associated with poorer health and increased cost. The aim of this study was to investigate the prevalence and ingredient cost of comorbidity in patients ≥ 65 years ... -
A prospective investigation of predictive and modifiable risk factors for breast cancer in unaffected BRCA1 and BRCA2 gene carriers
BENNETT, KATHLEEN (2013)Background Breast cancer is the most common female cancer worldwide. The lifetime risk of a woman being diagnosed with breast cancer is approximately 12.5%. For women who carry the deleterious mutation in either of the ... -
Supporting the improvement and management of prescribing for urinary tract infections (SIMPle): protocol for a cluster randomized trial
BENNETT, KATHLEEN (2013)Background The overuse of antimicrobials is recognized as the main selective pressure driving the emergence and spread of antimicrobial resistance in human bacterial pathogens. Urinary tract infections (UTIs) are among ...