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Recent Submissions

  • Risk markers for acute stroke in Ireland - association of sodium-lithium countertransport (SLC) with vascular disease 

    Collins, Daniel Ronan (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Pharmacology & Therapeutics, 2002)
    The work in this thesis is divided into two parts, an epidemiological study of the risk markers for stroke in an Irish population and a laboratory study of the possible association between sodium lithium countertransport ...
  • β-adrenoceptor-mediated regulation of matrix metalloproteinase-9 in fibroblasts 

    Rietz, Anne (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Pharmacology & Therapeutics, 2011)
    Adrenoceptor signalling in fibroblasts: Intracellular cAMP levels were measured by a direct cAMP enzyme immunoassay. Isoprenaline (ISO, 1 μM) increased intracellular cAMP concentration by 1.3 and 4.8 fold, P<0.05, after ...
  • Health technology assessment in the Irish healthcare setting : application to oral anticoagulants 

    McCullagh, Laura M. (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Pharmacology & Therapeutics, 2012)
    The objective of this thesis was to examine the application of economic evaluation within the Irish healthcare setting. In so doing, the author sought to develop skills in indirect comparison, economic modelling, value of ...
  • Genetic polymorphisms and arterial stiffness 

    Zhou, Sixiang (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Pharmacology & Therapeutics, 2008)
    Arterial stiffness exerts a major influence on cardiac afterload and coronary perfusion. Indices of arterial stiffness have therefore been proposed as surrogate markers of cardiovascular risk and as potential therapeutic ...
  • Pharmacoepidemiology of diabetes mellitus in a national population 

    Zaharan, Nur Lisa (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Pharmacology & Therapeutics, 2010)
    Diabetes is associated with significant morbidity and mortality from microvascular and macrovascular complications. It is projected that the prevalence of diabetes will increase worldwide especially in the elderly population ...

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