Browsing School of Genetics & Microbiology by Author "O'Brien, Siobhan"
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Community composition drives siderophore dynamics in multispecies bacterial communities.
O'Brien, Siobhan (2023)Background Intraspecific public goods are commonly shared within microbial populations, where the benefits of public goods are largely limited to closely related conspecifics. One example is the production of iron-scave ... -
Cultivating antimicrobial resistance: how intensive agriculture ploughs the way for antibiotic resistance
O'Brien, Siobhan (2023)Antimicrobial resistance (AMR) is a growing threat to public health, global food security and animal welfare. Despite efforts in antibiotic stewardship, AMR continues to rise worldwide. Anthropogenic activities, particularly ... -
Development of liquid culture media mimicking the conditions of sinuses and lungs in cystic fibrosis and health
O'Brien, Siobhan (2022)The respiratory tract is a compartmentalised and heterogenous environment. The nasopharynx and sinuses of the upper airways have distinct properties from the lungs and these differences may shape bacterial adaptation ... -
Ecological dependencies and the illusion of cooperation in microbial communities
O'Brien, Siobhan (2024)Ecological dependencies - where organisms rely on other organisms for survival - are a ubiquitous feature of life on earth. Multicellular hosts rely on symbionts to provide essential vitamins and amino acids. Legume plants ... -
Ecological selection of siderophore-producing microbial taxa in response to heavy metal contamination
O'Brien, Siobhan (2018)Some microbial public goods can provide both individual and community-wide benefits, and are open to exploitation by non-producing species. One such example is the production of metaldetoxifying siderophores. Here, we ... -
No effect of intraspecific relatedness on public goods cooperation in a complex community
O'Brien, Siobhan (2018)Many organisms—notably microbes—are embedded within complex communities where cooperative behaviors in the form of excreted public goods can benefit other species. Under such circumstances, intraspecific interactions are ... -
Resource heterogeneity and the evolution of public goods cooperation
O'Brien, Siobhan (2020)Heterogeneity in resources is a ubiquitous feature of natural landscapes affecting many aspects of biology. However, the effect of environmental heterogeneity on the evolution of cooperation has been less well studied. ... -
Species interactions drive the spread of ampicillin resistance in human-associated gut microbiota
O'Brien, Siobhan (2021)Background and objectives: Slowing the spread of antimicrobial resistance is urgent if we are to continue treating infectious diseases successfully. There is increasing evidence microbial interactions between and within ... -
Stress causes interspecific facilitation within a compost community
O'Brien, Siobhan (2021)Ecological theory predicts interactions between species to become more positive under abiotic stress, while competition should prevail in more benign environments. However, experimental tests of this stress gradient ...