Browsing Pharmacy and Pharmaceutical Sciences (Scholarly Publications) by Title
Now showing items 419-438 of 445
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Targeting the noradrenergic system for anti-inflammatory and neuroprotective effects: implications for Parkinson's disease.
(2018)Degeneration of the locus coeruleus noradrenergic system is thought to play a key role in the pathogenesis of Parkinson’s disease (PD), whereas pharmacological approaches to increase noradrenaline bioavailability may ... -
Titanium dioxide nanoparticles enhance production of superoxide anion and alter the antioxidant system in human osteoblast cells
(2015)Titanium dioxide (TiO2) nanoparticles (NPs) are manufactured worldwide for a variety of engineering and bioengineering applications. TiO2NPs are frequently used as a material for orthopedic implants. However, to the best ... -
Traditional Chinese Medicine: From Aqueous Extracts to Therapeutic Formulae
(IntechOpen, 2019)Traditional Chinese medicine (TCM) is one of the most established systems of medicine in the world. The therapeutic formulae used in TCM are frequently derived from aqueous decoctions of single plants or complex multicomponent ... -
Transport of the fluorescent organic cation 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide (ASP+) in human respiratory epithelial cells
(2012)Organic cation/carnitine transporters (OCT/N) mediate uptake of positively charged molecules. Their role in lung epithelium, however, is not well understood. OCT/N expression and activity was studied in cell lines of human ... -
Troglitazone attenuates TGF-β1-induced EMT in alveolar epithelial cells via a PPARγ-independent mechanism
(2012)Peroxisome proliferator activated receptor ? (PPAR?) agonists are effective antifibrotic agents in a number of tissues. Effects of these agents on epithelial-mesenchymal transition (EMT) of primary alveolar epithelial cells ... -
Tumour vasculature targeting agents in hybrid/conjugate drugs.
(2013)Tumour vasculature targeting has been a very active area of cancer drug discovery over the last decade. Growth of solid tumours beyond a certain point requires a sufficient blood supply in order for them to develop and ... -
Twenty-first century mast cell stabilizers
(2013)Mast cell stabilizing drugs inhibit the release of allergic mediators from mast cells and are used clinically to prevent allergic reactions to common allergens. Despite the relative success of the most commonly prescribed ... -
Understanding the Carbon-Bio Interface: Influence of Surface Chemistry and Buffer Composition on the Adsorption of Phospholipid Liposomes at Carbon Surfaces
(2020)Surface active phospholipids are present in fluids of biological relevance, and their adsorption may condition and determine the response of carbon and nanocarbon surfaces when they are immersed in physiological media. In ... -
Unintended discontinuation of medication following hospitalisation: a retrospective cohort study
(BMJ Publishing Group, 2019)Objectives: Whether unintended discontinuation of common, evidence-based, long-term medication occurs after hospitalisation; what factors are associated with unintended discontinuation; and whether the presence of documentation ... -
A Unique Polysaccharide containing 3-O-Methylarabinose and 3-O-Methylgalactose from Tinospora sinensis
(2018)Tinospora sinensis (Lour.) Merrill is of great therapeutic significance in Indian traditional medicine. Crude polysaccharides were isolated from methanol pre-extracted stems of dried material by successive extractions with ... -
Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles
(2021)The minimal information for studies of extracellular vesicles (EVs, MISEV) is a field-consensus rigour initiative of the International Society for Extracellular Vesicles (ISEV). The last update to MISEV, MISEV2018, was ... -
Upgrading Methylation Method for Structural Studies of Polysaccharides: Case Analysis of a Bioactive Polysaccharide from Acacia tortilis.
(2020)Methylation has been the most widely used conventional tool in the structural characterization of polysaccharides. In the series of developments in methylation methods employing a diverse range of solvents and methylating ... -
The Use of Proton Pump Inhibitors Among Older Adults with Intellectual Disability: A Cross Sectional Observational Study.
(2018)Background: Older people with Intellectual Disability (ID) have a high prevalence of gastrointestinal conditions such as Gastro-Oesophageal Reflux Disease (GORD). However, despite this, information about treatment, in ...
