Browsing Mechanical & Manufacturing Eng (Theses and Dissertations) by Sponsor "Trinity College Dublin (TCD)"
Now showing items 1-4 of 4
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3D Bioprinted Cartilaginous Templates as Developmentally Inspired Implants for Large Bone Defect Regeneration
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)Whilst bone possesses an inherent capacity for regeneration, defects above a critical size cannot heal on their own. Damaged or diseased bone can be treated using autografts or a range of different bone grafting biomaterials, ... -
Development of a performance framework to support the innovation process
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)Performance frameworks (PFs) for measuring the innovation process are critical for both research and practice. However, existing PFs neglect performance indicators (PIs) and dimensions relevant to companies' current ... -
Measuring physical function in Amyotrophic Lateral Sclerosis: Novel solutions to an old problem
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2023)Sensitive, objective outcome measures are essential for tracking clinical severity in neurodegenerative conditions such as Amyotrophic Lateral Sclerosis or Parkinson’s Disease. The current ‘gold standard’ multi-item rating ... -
Non-Invasive metabolic profiling in tissue engineering and innate immunology by 2P-FLIM
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2023)During the golden age of biochemistry from 1920s to 1960s, many of the metabolic pathways responsible for nutrient usage and energy production in humans and other organisms was defined. During this period, glycolysis, Krebs ...