Browsing Mechanical & Manufacturing Eng (Theses and Dissertations) by Title
Now showing items 21-40 of 219
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An asperity deformation model for the sliding cylinder problem : theoretical and experimental investigations
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2000)Statistical analysis shows that the main reason for the failure of machines is not breakage but wear of the moving parts resulting from rubbing stress. Although the laws of friction are fairly well substantiated, there are ... -
An experimental and 3D finite element analysis of a form rolling process
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2005)This thesis investigates a cold forming process called Form Rolling. Form Rolling is an innovative method of producing near-net shape parts, which is being implemented in particular by fastener manufacturers. In this study, ... -
An experimental and numerical investigation into the machining of Inconel 718 using coated cemented carbide cutting tools
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2000)The nickel-base superalloy Inconel 718, a tough material capable of maintaining its strength at high temperatures and resisting corrosion in various environments, can be classified as a "difficult to machine" material. Yet ... -
An improved framework for the inverse analysis of skeletal muscle tissue in-vivo
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2012)This thesis focusses on the development of an experimental and computational framework for the non-invasive analysis of the passive mechanical properties of living human skeletal muscle tissue. This is relevant to many ... -
An investigation into the causes of higher rates of restenosis in peripheral arteries compared with coronary arteries following stenting
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2010)The use of stenting in peripheral arteries has been limited by rates of in-stent restenosis and stent fracture considerably higher than seen in coronary arteries. Traditional balloon expandable stainless steel stents were ... -
An investigation into the influence of cardiovascular stent design on the development of restenosis using the finite element method
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2004)Finite element models, which can determine the degree of vascular injury caused to a vessel by a stent and hence ascertain the propensity of that stent design to cause in¬stent restenosis, would be a valuable tool for both ... -
An investigation into the role of substrate stiffness and oxygen availability in the regulation of stem cell differentiation during tissue regeneration
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2013)Mesenchymal stem cells (MSCs) are multipotent cells which can differentiate down multiple lineages and potentially generate tissues such as cartilage, bone or adipose tissue. It is becoming increasingly clear that mechanical ... -
An investigation of joint tissue derived stem cells for articular cartilage tissue engineering
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2011)Tissue engineering has emerged as a promising approach to repair damaged articular cartilage. The associated drawbacks with the isolation and expansion of chondrocytes from autologous tissue have prompted significant ... -
An investigation of structure-function relations in articular cartilage during skeletal maturation
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2013)The over-riding objective of this thesis was to build upon our current understanding of the evolving nature of articular cartilage mechanics by elucidating how changes to structure and composition of the tissue during ... -
Analysis of noise source mechanisms for a subsonic jet
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2006)Despite advances in engine design, from high bypass to co-axial or lobe shaped nozzles, the problem of jet noise reduction continues to require ongoing research in order to comply with the criteria inherent in environmental ... -
Analysis of the elastic and inelastic behaviour of healthy and diseased arterial tissue
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2012)Mechanical factors play a key role in determining the success of clinical procedures such as balloon angioplasty and stenting that aim to increase lumen size in atherosclerotic lesions. Finite element modelling is commonly ... -
Aspects of the fatigue behaviour of acrylic bone cement
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2002)Polymethylmethacrylate bone cement is used to fixate many orthopaedic implants. However, it is a brittle material, prone to damage accumulation leading to cement cracking and prosthesis loosening. The damage accumulation ... -
BIOFABRICATION STRATEGIES TO GUIDE THE SELF-ORGANISATION OF BIOMIMETIC CARTILAGE AND OSTEOCHONDRAL TISSUES
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)The modest clinical impact of musculoskeletal tissue engineering (TE) can be attributed, at least in part, to a failure to recapitulate the structure, composition and functional properties of the target tissue. This has ... -
Biomechanical origins of osteoporosis
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2004)The contention of this thesis is that a pathological change in bone tissue material properties during osteoporosis ahers the mechanical stimuli to bone remodelling cells and drives them to adapt the trabecular architecture ...