Browsing Clinical Medicine (Scholarly Publications) by Subject "TGF-beta 1"
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IHG-1 must be localised to mitochondria to decrease Smad7 expression and amplify TGF-β1-induced fibrotic responses
(2013)TGF -β1 is a prototypic profibrotic cytokine and major driver of fibrosis in the kidney and other organs. Induced in high glucose-1 ( IHG-1) i s a mitochondrial protein which we have recently reported to be associated ...