Browsing Clinical Medicine (Scholarly Publications) by Subject "T-cells"
Now showing items 1-4 of 4
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Advances in siRNA delivery to T-cells: potential clinical applications for inflammatory disease, cancer and infection.
(2013)The specificity of RNAi and its ability to silence 'undruggable' targets has made inhibition of gene expression in T-cells with siRNAs an attractive potential therapeutic strategy for the treatment of inflammatory disease, ... -
Sphingosine-1-phosphate receptor modulator FTY720 attenuates experimental myeloperoxidase-ANCA vasculitis in a T cell-dependent manner
(2020)Sphingosine-1-phosphate (S1P) is a pleiotropic lysosphingolipid derived from the metabolism of plasma membrane lipids. The interaction between S1P and its ubiquitously expressed G-protein-coupled receptors (S1PR1-5) is ...