Browsing Clinical Medicine (Scholarly Publications) by Subject "Oncology"
Now showing items 1-8 of 8
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Epigenetic Regulation of Glucose Transporters in Non-Small Cell Lung Cancer
(MDPI, 2011)Due to their inherently hypoxic environment, cancer cells often resort to glycolysis, or the anaerobic breakdown of glucose to form ATP to provide for their energy needs, known as the Warburg effect. At the same time, ... -
Epigenetics Underpinning the Regulation of the CXC (ELR+) Chemokines in Non-Small Cell Lung Cancer
(PLoS, 2011)Background: Angiogenesis may play a role in the pathogenesis of Non-Small Cell Lung cancer (NSCLC). The CXC (ELR+) chemokine family are powerful promoters of the angiogenic response. Methods: The expression of the CXC ... -
Receptor tyrosine kinases and their activation in melanoma.
(2011)Receptor tyrosine kinases (RTKs) and their downstream signalling pathways have long been hypothesized to play key roles in melanoma development. A decade ago, evidence was derived largely from animal models, RTK expression ... -
The Role of Epigenetics in Resistance to Cisplatin Chemotherapy in Lung Cancer
(2011)Non-small cell lung cancer (NSCLC) is the most common cause of cancer related death in the world. Cisplatin and carboplatin are the most commonly used cytotoxic chemotherapeutic agents to treat the disease. These agents, ... -
The role of epigenetics in resistance to cisplatin chemotherapy in lung cancer
(2011)Non-small cell lung cancer (NSCLC) is the most common cause of cancer related death in the world. Cisplatin and carboplatin are the most commonly used cytotoxic chemotherapeutic agents to treat the disease. These agents, ...