Browsing Clinical Medicine (Scholarly Publications) by Author "Palsson Mcdermott, Eva"
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Pyruvate Kinase M2 Regulates Hif-1alfa Activity and IL-1? Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages.
Palsson Mcdermott, Eva; Keane, Joseph; O'Neill, Luke; Sheedy, Frederick; Johnston, Daniel; Gleeson, Laura (2015)TLR4-activated macrophages switch their metabolism from oxidative phosphorylation to glycolysis to rapidly provide for the high energy and biosynthetic demands of infection or injury response. Palsson-McDermott identify ...