Browsing Clinical Medicine (Scholarly Publications) by Author "KENNEDY, MICHAEL"
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Cancer risks for BRCA1 and BRCA2 mutation carriers: Results from prospective analysis of EMBRACE
KENNEDY, MICHAEL (2013)Background Reliable estimates of cancer risk are critical for guiding management of BRCA1 and BRCA2 mutation carriers. The aims of this study were to derive penetrance estimates for breast cancer, ovarian cancer, ... -
Effect of BRCA Mutations on Metastatic Relapse and Cause-specific Survival After Radical Treatment for Localised Prostate Cancer
KENNEDY, MICHAEL (2015)Background: Germline BRCA mutations are associated with worse prostate cancer (PCa) outcomes; however, the most appropriate management for mutation carriers has not yet been investigated. Objective: To evaluate the ... -
Optimally tolerated dose of lapatinib in combinationwith docetaxel plus trastuzumab in first-line treatmentof HER2-positive metastatic breast cancer
KENNEDY, MICHAEL (2013)Background: This phase IB, open-label, dose-escalation study evaluated the safety, tolerability, and optimally tolerated regimen (OTR) of lapatinib in combination with docetaxel and trastuzumab in patients with ...