Browsing Clinical Medicine (Theses and Dissertations) by Subject "nanomedicine"
Now showing items 1-3 of 3
-
Development of a novel CD52 functionalised nanoparticle for the targeting of Chronic Lymphocytic Leukaemia
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2019)Nanomedicine has been recognised as a next-generation technology for the treatment and management of many disease states, including blood cancers. The term nanotechnology was first coined in 1974 and, is at the interface ... -
Synthesis and characterisation of aerosolised MIF inhitibitors for the treatment of respiratory disease
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2019)The main focus of this PhD thesis was to investigate the synthesis and characterisation of an aerosolised poly lactic-co-glycolic acid (PLGA) nanodrug delivery system for MIF enzyme inhibitors to modulate the physiological ... -
Three-dimensional (3D) hepatic cell culture models to improve the clinical translation of nanobiomaterials (NBMs)
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2021)Despite the wide-reaching applications of nanoparticles that may be used for medical applications, i.e. nanobiomaterials or NBMs, in human health and medicine, their translation to the clinic is staggering slow, with a ...