Browsing Clinical Medicine (Theses and Dissertations) by Subject "Enzalutamide"

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    • Molecular Evaluation of Enzalutamide Resistance in Prostate Cancer 

      AIRD, JOHN (Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2020)
      Prostate cancer is a leading cause of cancer related death in men. As prostate cancer cells are dependent on androgen receptor (AR) signalling for continued growth, anti-androgen therapy is initially effective in treating ...

    • Novel Mechanisms of Resistance to Enzalutamide in Prostate Cancer 

      Lim, Marvin Chang (Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)
      Prostate cancer (PCa) is the second most common invasive cancer in men worldwide. In Ireland, PCa is the third leading cause of male cancer related mortality. AR directed therapies have remained the primary therapeutic ...