Browsing Clinical Medicine (Theses and Dissertations) by Author "Rudolph, Christine"
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Investigation of the role of RACKI in T lymphocyte migration
Rudolph, Christine (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2012)Induction of the innmune response and production of pro-inflammatory cytokines results in the upregulation of ICAM-1 expressed on endothelial cells. Binding of ICAM-1 to the β2 integrin receptor LFA-1 on T cells induces T ...