Browsing Clinical Medicine (Theses and Dissertations) by Author "Finnucane, Orla"
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The pathogenic role of macrophage migration inhibitory factor in high-fat diet induced insulin resistance
Finnucane, Orla (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2012)Adipose tissue inflammation is central to the pathogenesis of obesity associated insulin resistance (IR), type 2 diabetes mellitus (T2DM) and hepatic steatosis. High-fat diet (HFD)-induced adipose tissue expansion is ...