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  • Investigating chromatin remodelling by the Swi-Snf and Tup1-Cyc8 complexes 

    AL-HUSSAIN, MOHAMED MUBARAK (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Microbiology, 2020)
    Swi-Snf is an ATP-dependent chromatin remodelling complex which generally acts as a co-activator of gene transcription via its removal of promoter nucleosomes. Conversely, Tup1-Cyc8 (Ssn6) is a co-repressor complex which ...