Browsing Medical Gerontology (Scholarly Publications) by Subject "Physical disability"
Now showing items 1-20 of 36
-
Approximate entropies of resting state continuous neurocardiovascular physiological signals are associated with physical frailty in older adults
(2021)Frailty in older adults is characterised by dysregulation in multiple physiological systems. The frailty phenotype is defined on the basis of exhaustion, unexplained weight loss, weakness, slowness and low physical activity ... -
Associations between Cardiovascular Signal Entropy and Cognitive Performance over Eight Years
(2021)In this study, the relationship between non-invasively measured cardiovascular signal entropy and global cognitive performance was explored in a sample of community-dwelling older adults from The Irish Longitudinal Study ... -
Associations between neurocardiovascular signal entropy and physical frailty
(2021)In this cross-sectional study, the relationship between noninvasively measured neurocardiovascular signal entropy and physical frailty was explored in a sample of community-dwelling older adults from The Irish Longitudinal ... -
Biomarker Signatures of Two Phenotypical Pre-Frailty Types in The Irish Longitudinal Study on Ageing
(2022)Abstract: We investigated the biomarker signatures of two previously reported phenotypical prefrailty (PF) types in the first wave of The Irish Longitudinal Study on Ageing (TILDA): PF1 (unexplained weight loss and/or ... -
Building resilience and reversing frailty: a randomised controlled trial of a primary care intervention for older adults
(2023)Background: There is a need for effective primary care interventions that help older people combat frailty and build resilience. Objective: To study the effectiveness of an optimised exercise and dietary protein ... -
Cardiovascular signal entropy predicts all-cause mortality: evidence from The Irish Longitudinal Study on Ageing (TILDA)
(2022)In this study, the relationship between cardiovascular signal entropy and the risk of seven-year all-cause mortality was explored in a large sample of community-dwelling older adults from The Irish Longitudinal Study on ... -
Characterising the Blood Pressure Response to Physical Counterpressure Manoeuvres Using Surface Electromyography in Adults with Long Covid
(2023)Objective: Orthostatic intolerance (OI) is common in Long Covid. Physical counterpressure manoeuvres (PCM) may improve OI in other disorders. We characterised the blood pressure-rising effect of PCM using surface ... -
Clinical clustering of eight orthostatic haemodynamic patterns in The Irish Longitudinal Study on Ageing (TILDA)
(2020)Background: Orthostatic hypotension (OH) can be assessed with non-invasive continuous beat-to-beat haemodynamic monitoring during active stand (AS) testing; this yields large volumes of data outside the scope ... -
Comparison of gait speed reserve, usual gait speed, and maximum gait speed of adults aged 50+ in Ireland using explainable machine learning
(2021)Gait speed is a measure of general fitness. Changing from usual (UGS) to maximum (MGS) gait speed requires coordinated action of many body systems. Gait speed reserve (GSR) is defined as MGS–UGS. From a shortlist of 88 ... -
Core requirements of frailty screening in the emergency department:an international Delphi consensus study
(2023)Introduction: Frailty is associated with adverse outcomes among patients attending emergency departments (EDs). While multiple frailty screens are available, little is known about which variables are important to incorporate ... -
COVID-19 deaths in Irish Nursing Homes: exploring variation and association with the adherence to national regulatory quality standards
(CPEC-LSE, 2020)The COVID-19 pandemic has disproportionately affected nursing home residents worldwide, with Ireland having one of the highest reported proportions of COVID-19 deaths in this setting. In Ireland, the publication of a ... -
Do The Frail Experience More Adverse Events From Intensive Blood Pressure Control? A 2-Year Prospective Study In The Irish Longitudinal Study On Ageing (TILDA)
(2022)Background: The 2018 European Society of Cardiology/European Society of Hypertension (ESC/ESH) guidelines for management of hypertension in adults aged ≥65 years recommend a blood pressure (BP) treatment target of 130–139/70–79 ... -
Exploring bi-directional temporal associations between timed-up-and-go and cognitive domains in The Irish Longitudinal Study on Ageing (TILDA)
(2022)Introduction: The bi-directional longitudinal associations between mobility and cognition in older adults are poorly understood. Our objective was to study the temporal associations between timed-up-and-go (TUG) and five ... -
Hospital-associated deconditioning: not only physical, but also cognitive
(2022)Introduction Hospital-associated deconditioning (HAD) or post-hospital syndrome is well recognized as reduced functional performance after an acute hospitalization. Recommendations for the management of HAD are still ... -
The Importance of Age in the Prediction of Mortality by a Frailty Index: A Machine Learning Approach in the Irish Longitudinal Study on Ageing
(2021)The quantification of biological age in humans is an important scientific endeavor in the face of ageing populations. The frailty index (FI) methodology is based on the accumulation of health deficits and captures variations ... -
The Lived Experience of Frailty: Beyond Classification and Towards a Holistic Understanding of Health
(2024)Purpose: Frailty is characterised by decreased physiological reserves and vulnerability to stressors. Although scales such as the Fried’s Frailty Phenotype (FP), Frailty Index (FI), and Clinical Frailty Scale (CFS) are ... -
Longitudinal study on Sustained Attention to Response Task (SART): clustering approach for mobility and cognitive decline
(2022)The Sustained Attention to Response Task (SART) is a computer-based go/no-go task to measure neurocognitive function in older adults. However, simplified average features of this complex dataset lead to loss of primary ... -
Network Physiology in Aging and Frailty: The Grand Challenge of Physiological Reserve in Older Adults
(2021)In this Specialty Grand Challenge, we outline our vision of the current challenges in the field of Network Physiology as applied to aging and frailty. An expected development in this field for the 21st century is the ...