Browsing Medical Gerontology (Scholarly Publications) by Author "Romero-Ortuno, Roman"
Now showing items 1-20 of 122
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ACE gene I/D polymorphism and severity of SARS-CoV-2 infection in hospitalized patients: a metanalysis
Romero-Ortuno, Roman (2021)Background Hypertension and type 2 diabetes increase the risk of severe SARS-CoV-2 infection. On the other hand, homozygous ACE deletion polymorphism (DD) has been associated with these two diseases and risk of acute ... -
ACUTE-PHASE BED-REST DURATIONWAS ASSOCIATED WITH LOWER GRIP STRENGTH IN A POST-COVID-19 COHORT
Romero-Ortuno, Roman (2021) -
Admissions for Orthostatic Hypotension: an Analysis of NHS England Hospital Episode Statistics Data
Romero-Ortuno, Roman; Kenny, Rose (2019)Objectives To determine whether admissions for orthostatic hypotension (OH) and its consequences, such as falls, have changed over the past 10 years in the National Health Service (NHS) England. Setting Data from NHS ... -
Alluvial visualization and computation of probabilities of transitions in frailty index states over an 8-year period using multi-state Markov models
Romero-Ortuno, Roman; Knight, Silvin (2021)The Frailty Index (FI) is an operationalization of frailty in older adults based on the accumulation of health deficits. FI cut-offs define the non-frail, prefrail and frail states. We described longitudinal transitions ... -
Angiotensin-Converting Enzyme (ACE) genetic variation and longevity in Peruvian older people: a cross-sectional study
Romero-Ortuno, Roman; Oscanoa, Teodoro J.; Cieza, Edwin C.; Lizaraso-Soto, Frank A.; Guevara, María L.; Fujita, Ricardo M. (2020)Background: Some studies have suggested that the insertion(I)/deletion(D) polymorphism of the Angiotensin-Converting Enzyme (ACE) gene may be associated with human longevity, especially in centenarians. However, this ... -
Anticholinergic medications in patients admitted with cognitive impairment and falls (AMiCI). The impact of hospital admission on anticholinergic cognitive medication burden. Results of a multi centre observational study
Romero-Ortuno, Roman (2018)What is known and objective: Drugs with anticholinergic properties increase the risk of falls, delirium, chronic cognitive impairment, and mortality and counteract procholinergic medications used in the treatment of dementia. ... -
Approximate entropies of resting state continuous neurocardiovascular physiological signals are associated with physical frailty in older adults
Romero-Ortuno, Roman; Knight, Silvin (2021)Frailty in older adults is characterised by dysregulation in multiple physiological systems. The frailty phenotype is defined on the basis of exhaustion, unexplained weight loss, weakness, slowness and low physical activity ... -
The association between clinical frailty and walking speed in older hospitalised medical patients: a retrospective observational study
Romero-Ortuno, Roman (2017)This study aims to further evaluate the use of the clinical frailty scale (CFS) by assessing its correlation with usual walking speed (UWS) in older medical inpatients. Methods Retrospective observational study in an English ... -
The association between cognitive impairment and functional outcome in hospitalised older patients: a systematic review and meta-analysis
Romero-Ortuno, Roman (2017)Background: in hospitalised older adults, cognitive impairments are common and may be associated with functional outcomes. Our aim was to systematically review this association.Method: we systematically searched MEDLINE, ... -
Association between low serum vitamin d and Increased mortality and severity due to COVID-19: reverse causality?
Romero-Ortuno, Roman (2022)We are very close to completing two years since the start of the COVID-19 pandemic. Even though vaccines have been developed and applied to more than 4 billion people in the world, SARS-CoV-2 continues to be a challenge ... -
Association of cognition with functional trajectories in patients admitted to geriatric wards: a retrospective observational study
Romero-Ortuno, Roman (2017)Aim: Impaired cognition is common among older patients admitted to acute hospitals, but its association with functional trajectories has not been well studied. Methods: A retrospective observational study was carried ... -
The association of geriatric syndromes with hospital outcomes
Romero-Ortuno, Roman (2017)BACKGROUND: Frailty, history of dementia (HoD), and acute confusional states (ACS) are common in older patients admitted to hospital. OBJECTIVE: To study the association of frailty (≥6 points in the Clinical Frailty Scale ... -
Association of the Frailty Index with structural brain volumes in The Irish Longitudinal Study on Ageing (TILDA)
Romero-Ortuno, Roman; Knight, Silvin (2022) -
Associations between Cardiovascular Signal Entropy and Cognitive Performance over Eight Years
Romero-Ortuno, Roman; Knight, Silvin; Kenny, Rose; Newman, Louise (2021)In this study, the relationship between non-invasively measured cardiovascular signal entropy and global cognitive performance was explored in a sample of community-dwelling older adults from The Irish Longitudinal Study ... -
Associations between neurocardiovascular signal entropy and physical frailty
Romero-Ortuno, Roman; Knight, Silvin; Kenny, Rose; Newman, Louise (2021)In this cross-sectional study, the relationship between noninvasively measured neurocardiovascular signal entropy and physical frailty was explored in a sample of community-dwelling older adults from The Irish Longitudinal ... -
ASSOCIATIONS OF FRAILTY WITH CONSECUTIVE GAIT SPEED TRAILS MEASURED BOTH WITH AND WITHOUT ADDITIONAL STRESSORS
Romero-Ortuno, Roman (2021) -
Biomarker Signatures of Two Phenotypical Pre-Frailty Types in The Irish Longitudinal Study on Ageing
Romero-Ortuno, Roman; O'Halloran, Aisling (2022)Abstract: We investigated the biomarker signatures of two previously reported phenotypical prefrailty (PF) types in the first wave of The Irish Longitudinal Study on Ageing (TILDA): PF1 (unexplained weight loss and/or ... -
Biomarkers of delirium risk in older adults: a systematic review and meta-analysis
Romero-Ortuno, Roman (2023)Delirium is a neuropsychiatric syndrome associated with increased morbidity and mortality in older patients. The aim of this study was to review predictive biomarkers of delirium in older patients to gain insights into ... -
Blood Pressure Signal Entropy as a Novel Marker of Physical Frailty: Results from the FRAILMatics Clinical Cohort
Romero-Ortuno, Roman; Knight, Silvin (2022)In this study we investigated the association between information entropy in short length blood pressure signals and physical frailty status, in a group of patients aged 50+ recruited from the Falls and Syncope Unit at ...