RSS 1.0Medical Gerontology (Theses and Dissertations)
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Exploring Novel Biomarkers of Brain Health in Midlife Type 2 Diabetes Mellitus (ENBIND)
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2020)Type 2 Diabetes Mellitus (T2DM) in midlife (between the ages of 35-65) is associated with a two-fold increased risk of dementia in later life. Despite this, knowledge around the pathophysiological mechanisms linking T2DM ... -
Ageing outcomes in women and men in Ireland: the role of the religious social context
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2020)Aim & background: The aim of this thesis is to explore how the religious social context in Ireland has helped shape the health and ageing outcomes of older women and men. Understanding the factors behind the ability to ... -
The Association between Blood Pressure, Cerebral Perfusion and Late Life Depression
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2020)Background: While late life is generally characterised by contentment and happiness, depression in later life confers an independently increased risk of early mortality, cognitive and functional decline and nursing home ... -
Cardiovascular Autonomic Nervous System, Blood Pressure Instability and Brain Health in Older Adults: Population-Based Perspectives
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2019)The aim of this thesis is to provide new insights into the shared pathways by which the cardiovascular autonomic nervous system underpins optimal regulation of affect and cognitive function in older adults. Ageing is ... -
The Effects of Acute and Chronic Exercise on Brain Derived Neurotrophic Factor and Cognitive Performance in Mild Cognitive Impairment
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2019)Introduction: Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin that supports neural survival, growth and synaptic plasticity and is upregulated through exercise. While the exact neuronal mechanisms underlying the ...
