Medical Gerontology (Theses and Dissertations)
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An evaluation ofthe Allostatic Load framework for quantifying differences inhealth and longevity
(Trinity College Dublin. School of Medicine. Discipline of Medical Gerontology, 2023)The Allostatic Load (AL) framework posits that chronic or repeated exposure to stressors can cause dysregulation of multiple interrelated physiological systems, which if prolonged, may ultimately lead to deteriorations in ... -
Identification of predictors of gait speeds in The Irish Longitudinal Study on Ageing using automated feature selection and explainable machine learning
(Trinity College Dublin. School of Medicine. Discipline of Medical Gerontology, 2023)This work reports the novel application of automated feature selection and explainable machine learning to identify and compare, in participants aged 50 years or over from wave 3 of The Irish Longitudinal Study on Ageing ... -
The Age-Old Question of ANCA-Associated Vasculitis
(Trinity College Dublin. School of Medicine. Medical Gerontology, 2023)Anti-Neutrophil Cytoplasmic Autoantibody (ANCA)-Associated Vasculitis (AAV) is a group of systemic autoimmune disorders characterised by severe inflammation of the small blood vessels. Unusually for an autoimmune disease, ... -
Clinical Decision Support for the Assessment of Syncope and Falls: Novel Applications of Cerebral Perfusion Measurement and Big Data Analytics
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2023)Syncope, defined as a transient loss of consciousness due to cerebral hypoperfusion, is common in both young and old, with syncope an attributable cause of unexplained falls (UF) in older adults. Both syncope and falls ... -
Determinants of Physical Activity Engagement and Physical Activity Intervention Adherence in Individuals with Mild Cognitive Impairment: A Mixed Methods Study
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2022)The overarching aim of this thesis was to to identify the determinants of PA engagement and PA intervention adherence in individuals with MCI to expand on this under-researched topic and better inform PA promotion and ...