Browsing Psychiatry (Scholarly Publications) by Title
Now showing items 104-123 of 361
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Effect of childhood maltreatment on brain structure in adult patients with major depressive disorder and healthy participants.
(2014)BACKGROUND: Childhood maltreatment has been found to play a crucial role in the development of psychiatric disorders. However, whether childhood maltreatment is associated with structural brain changes described for ... -
Effects of MIR137 on fronto-amygdala functional connectivity.
(2014)MIR137 is implicated in brain development and encodes a microRNA that regulates neuronal maturation and adult neurogenesis. Recently, a common genetic variant within MIR137 showed genome wide evidence of association with ... -
The effects of psychosis risk variants on brain connectivity: a review.
(2012)n light of observed changes in connectivity in schizophrenia and the highly heritable nature of the disease, neural connectivity may serve as an important intermediate phenotype for schizophrenia. However, how individual ... -
Effects of the neurogranin variant rs12807809 on thalamocortical morphology in schizophrenia.
(2013)Although the genome wide supported psychosis susceptibility neurogranin (NRGN) gene is expressed in human brains, it is unclear how it impacts brain morphology in schizophrenia. We investigated the influence of NRGN ... -
Electroconvulsive therapy - state of the art
(The Royal College of Physicians, 2003)Although electroconvulsive therapy (ECT) has been available for more than 60 years it is still the most acutely effective antidepressant treatment available (McCall, 2001). However, despite substantial advances in safety ... -
Electroconvulsive therapy, capacity and the law in Ireland.
(Irish Institute of Psychological Medicine, 2009)The Mental Health Act (MHA) 2001 has major implications for treating patients with electroconvulsive therapy (ECT), especially as those referred for treatment are among the most severely ill and often lose capacity. Under ... -
Enhancing studies of the connectome in autism using the autism brain imaging data exchange II
(2017)The second iteration of the Autism Brain Imaging Data Exchange (ABIDE II) aims to enhance the scope of brain connectomics research in Autism Spectrum Disorder (ASD). Consistent with the initial ABIDE effort (ABIDE I), that ... -
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.
(2014)The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. ... -
Epigenetic variance in dopamine D2 receptor: a marker of IQ malleability?
(2018)Genetic and environmental factors both contribute to cognitive test performance. A substantial increase in average intelligence test results in the second half of the previous century within one generation is unlikely to ... -
Epigenetics and depression: return of the repressed
(2014)Introduction: Epigenetics has recently emerged as a potential mechanism by which adverse environmental stimuli can result in persistent changes in gene expression. Epigenetic mechanisms function alongside the DNA sequence ... -
Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group
(2019)DNA methylation, which is modulated by both genetic factors and environmental exposures, may offer a unique opportunity to discover novel biomarkers of disease-related brain phenotypes, even when measured in other tissues ... -
Epistasis between neurochemical gene polymorphisms and risk for ADHD
(2011)A number of genes with function related to synaptic neurochemistry have been genetically associated with attention deficit/hyperactivity disorder. However, susceptibility to the development of common psychiatric disorders ... -
Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood
(Elsevier (Cell Press), 2018)Genetic correlation is a key population parameter that describes the shared genetic architecture of complex traits and diseases. It can be estimated by current state-of-art methods, i.e., linkage disequilibrium score ...