Browsing Physiology (Theses and Dissertations) by Subject "Alzheimer's Disease"
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Investigating the Effects of FTY720 on Spatial Memory and Neuroinflammation in a Rodent Model of Alzheimer's Disease
(Trinity College Dublin. School of Medicine. Discipline of Physiology, 2020)Alzheimer's disease (AD) is a progressive, age-related neurodegenerative disorder characterized by memory loss and cognitive decline, with loss of global functioning over time eventually leading to death. At the molecular ... -
Investigating the role of mechanosensitive channel Piezo1 in the CNS
(Trinity College Dublin. School of Medicine. Discipline of Physiology, 2019)All cells in the organism are able to sense changes in the mechanical properties of their environment, translating them into chemical intracellular signals through a process termed mechanotransduction, mostly via ...