Browsing Chemistry (Scholarly Publications) by Author "KELLY, JOHN"
Now showing items 1-8 of 8
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Direct observation by time-resolved infrared spectroscopy of the bright and the dark excited states of the [Ru(phen)2(dppz)]2+ light-switch compound in solution and when bound to DNA
KELLY, JOHN; GUNNLAUGSSON, THORFINNUR (2016)The [Ru(phen)2(dppz)]2+ complex (1) is non-emissive in water but is highly luminescent in organic solvents or when bound to DNA, making it a useful probe for DNA binding. To date, a complete mechanistic explanation for ... -
Excited state behaviour of substituted dipyridophenazine Cr(III) complexes in the presence of nucleic acids.
KELLY, JOHN (2010)The photophysics and photochemistry of [Cr(phen)2(dppz)]3+ and its 11,12-substituted derivatives [Cr(phen)2(X2dppz)]3+ {X = Me or F} have been studied in the presence of purine nucleotides or DNA using steady state and ... -
ps-TRIR Covers All the Bases - Recent Advances in the Use of Transient IR for the Detection of Ultrafast Species in DNA
KELLY, JOHN (2009)Recent developments of the picosecond transient absorption infrared technique and its ability to elucidate the nature and kinetic behaviour of transient species formed upon pulsed laser excitation of nucleic acids are described. -
Recent advances in the development of 1,8-naphthalimide based DNA targeting binders, anticancer and fluorescent cellular imaging agents.
KELLY, JOHN; BANERJEE, SWAGATA; GUNNLAUGSSON, THORFINNUR (2013)The development of functional 1,8-naphthalimide derivatives as DNA targeting, anticancer and cellular imaging agents is a fast growing area and has resulted in several such derivatives entering into clinical trials. This ... -
Substituted dipyridophenazine complexes of Cr(III): synthesis, enantiomeric resolution and binding interactions with calf thymus DNA.
KELLY, JOHN; MCCABE, THOMAS (2010)[Cr(phen)2(X2dppz)]3+ {X = H, Me, or F} have been synthesised, characterised, and chromatographically resolved into their constituent ? and ? enantiomers. The DNA-binding interactions of each of the racemic complexes were ... -
Synthesis and spectroscopic studies of chiral CdSequantum dots
GOUNKO, IOURI; KELLY, JOHN; GALLAGHER, SHANE (2010)Using microwave irradiation, water soluble, optically active, penicillamine (Pen) capped CdSenanocrystals with broad spectral distribution (430?780 nm) of photoluminescence have been produced and studied by a range of ... -
Transient Spectroscopy of Dipyridophenazine Metal Complexes which undergo electron transfer with DNA
KELLY, JOHN (2011)This review considers transient spectroscopic studies of electron transfer reactions between nucleic acids and the excited states of transition metal complexes containing dipyridophenazine or related ligands and focuses ... -
Understanding the DNA binding of novel non-symmetrical guanidinium/2-aminoimidazolinium derivatives.
KHAN, AMIR; ROZAS, ISABEL; O'DONOVAN, DANIEL HILLEBRAND; NAGLE, PADRAIC; KELLY, JOHN (2010)Biophysical studies have been carried out on a family of asymmetric guanidinium-based diaromatic derivatives to assess their potential as DNA minor groove binding agents. To experimentally assess the binding of these ...