dc.contributor.author | FOSTER, TIMOTHY | |
dc.date.accessioned | 2020-08-07T13:22:29Z | |
dc.date.available | 2020-08-07T13:22:29Z | |
dc.date.issued | 1979 | |
dc.date.submitted | 1979 | en |
dc.identifier.citation | Foster, T.J. and Nakahara, H., Deletions in the r-determinant mer region of plasmid R100-1 selected by loss of mercury hypersensitivity, Journal of Bacteriology, 1979, 140, 1, 301 - 305 | en |
dc.identifier.other | Y | |
dc.identifier.uri | | |
dc.identifier.uri | http://hdl.handle.net/2262/93128 | |
dc.description.abstract | A mutant of plasmid R100-1, which conferred cellular hypersensitivity to Hg2+ because of the insertion of Tn801 (TnA) into the gene determining synthesis of mercuric reductase enzyme, allowed further mutational events to be selected which resulted in either reversion to Hg2+ resistance (characteristic plasmid R100-1) or sensitivity at a level characteristic of plasmidless strains. Restriction endonuclease EcoRI and BamHI analysis showed that reversion to resistance resulted from loss of TnA from the R100-mer:Tn801 plasmid, whereas the change from hypersensitivity to sensitivity to Hg2+ usually resulted from deletion of part or all of Tn801 plus plasmid deoxyribonucleic acid sequences corresponding to the operator-proximal end of the mer operon. | en |
dc.format.extent | 301 | en |
dc.format.extent | 305 | en |
dc.language.iso | en | en |
dc.relation.ispartofseries | Journal of Bacteriology; | |
dc.relation.ispartofseries | 140; | |
dc.relation.ispartofseries | 1; | |
dc.rights | Y | en |
dc.subject | Hypersensitivity | en |
dc.subject | Synthesis | en |
dc.subject | Genes/Proteins | en |
dc.subject | Mercuric reductase | en |
dc.subject | Endonuclease EcoRI | en |
dc.title | Deletions in the r-determinant mer region of plasmid R100-1 selected by loss of mercury hypersensitivity | en |
dc.type | Journal Article | en |
dc.type.supercollection | scholarly_publications | en |
dc.type.supercollection | refereed_publications | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/tfoster | |
dc.identifier.rssinternalid | 1921 | |
dc.rights.ecaccessrights | openAccess | |
dc.identifier.rssuri | http://jb.asm.org/cgi/reprint/140/1/301?view=long&pmid=387727 | |