dc.contributor.author | O'Byrne, Robert | |
dc.date.accessioned | 2019-11-14T09:50:41Z | |
dc.date.available | 2019-11-14T09:50:41Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Robert O'Byrne, 'A study of the glycosylphosphatidylinositol phospholipase C in Trypanosoma brucei', [thesis], Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2013, pp 311 | |
dc.identifier.other | THESIS 10257 | |
dc.identifier.uri | http://hdl.handle.net/2262/90476 | |
dc.description.abstract | Trypanosoma brucei represents a clade of flagellated parasites that cause human
and animal trypanosomiases in sub-Saharan Africa. The glycosylphosphatidylinositol
phospholipase C (GPI-PLC) is an endogenous enzyme that has been shown to
contribute to the virulence of the parasite in vivo. Although the physiological role of
the GPI-PLC is currently unknown, the enzyme has been shown to hydrolyze the GPIanchor of the trypanosome's protective variant surface glycoprotein (VSG) coat under a number of experimental conditions. | |
dc.format | 1 volume | |
dc.language.iso | en | |
dc.publisher | Trinity College (Dublin, Ireland). School of Biochemistry and Immunology | |
dc.relation.isversionof | http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb15647224 | |
dc.subject | Biochemistry & Immunology, Ph.D. | |
dc.subject | Ph.D. Trinity College Dublin. | |
dc.title | A study of the glycosylphosphatidylinositol phospholipase C in Trypanosoma brucei | |
dc.type | thesis | |
dc.type.supercollection | thesis_dissertations | |
dc.type.supercollection | refereed_publications | |
dc.type.qualificationlevel | Doctoral | |
dc.type.qualificationname | Doctor of Philosophy (Ph.D.) | |
dc.rights.ecaccessrights | openAccess | |
dc.format.extentpagination | pp 311 | |
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