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  The Biochemical and Bioenergetic Consequences of the Myostatin SNP g.66493737C>T and SINE insertion 227 bp polymorphism in Skeletal Muscle of Thoroughbred Horses 

  Rooney, Mary F (2017)

  The Thoroughbred horse is a tremendous athletic breed, which can be attributed to years of genetic selection for speed and stamina. This selection has led to the Thoroughbred having a very high aerobic capacity relative ...
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  Helminth products promote anti-inflammatory trained innate immunity by imprinting long-term hematopoietic stem cells 

  Cunningham, Kyle (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2021)

  Recent research has shown that immunological memory is not confined to the cells of the adaptive immune system but can be imbued upon innate immune cells, including monocytes and macrophages, in a process known as trained ...
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  TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer 

  Finlay, David (2021)

  Background Natural killer (NK) cells provide important immune protection from cancer and are a key requirement for particular immunotherapies. There is accumulating evidence that NK cells become dysfunctional during cancer. ...
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  Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation 

  Finlay, David (2021)

  Fructose intake has increased substantially throughout the developed world and is associated with obesity, type 2 diabetes and non-alcoholic fatty liver disease. Currently, our understanding of the metabolic and mechanistic ...
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  The HCV protein, p7, suppresses inflammatory responses to TNF-a via STAT3 and ERK-mediated induction of SOCS3 

  Stevenson, Nigel (2019)

  Viruses use a spectrum of immune evasion strategies that enable infection and replication. The acute phase of hepatitis C virus (HCV) infection is characterized by nonspecific and often mild clinical symptoms, suggesting ...

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