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  The immunomodulatory properties of L-rhamnose 

  LUNDAHL, MIMMI LOUISE (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)

  L-Rhamnose is a non-mammalian monosaccharide ubiquitously found on the surface of both commensal and pathogenic bacteria. Previous publications had identified that L-rhamnose-rich Mycobacterium tuberculosis glycolipids, ...
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  Inflammasome Involvement in Barrett's and Oesophageal Adenocarcinoma 

  BARBER, GILLIAN LOUISE (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)

  Barrett's oesophagus is an inflammatory condition and a neoplastic precursor to oesophageal adenocarcinoma (OAC). Inflammasome signalling pathways contribute to acute and chronic inflammation, and can be enhanced by obesity. ...
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  Characterisation of the immune response to calcium phosphate particulates; implications for osteoarthritis and bone tissue engineering 

  MAHON, OLWYN (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)

  Early trauma, resulting in focal areas of cartilage damage with injury to the underlying subchondral bone (osteochondral damage) often progresses to arthritis. These so called osteochondral defects (OCDs) can arise from ...
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  A novel role of SOCS-4 and SOCS-5 in cytokine signalling 

  ALMOHAMMADI, DANIAH HAMEED (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)

  The immune system is propagated by cytokines and their intracellular signal transduction. To ensure an appropriate immune response, these signalling pathways are tightly controlled. One such regulatory mechanism is the ...
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  Mitochondrial localization of SESN2 

  Budanov, Andrei; Kovaleva, Irina E.; Tokarchuk, Artem V.; Zheltukhin, Andrei O.; Dalina, Alexandra A.; Safronov, Grigoriy G.; Evstafieva, Alexandra G.; Lyamzaev, Konstantin G.; Chumakov, Peter M. (2020)

  SESN2 is a member of the evolutionarily conserved sestrin protein family found in most of the Metazoa species. The SESN2 gene is transcriptionally activated by many stress factors, including metabolic derangements, reactive ...

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