A computational exploration of a possible alternative to nucleotides as the basis of a genetic alphabet
Citation:
Lavina Dewdney Ní Chaoimh, 'A computational exploration of a possible alternative to nucleotides as the basis of a genetic alphabet', [thesis], Trinity College (Dublin, Ireland). School of Chemistry, 2012, pp 230Download Item:
Abstract:
One of the most fundamental questions in molecular biology is why nature has chosen
Adenine (A), Cytosine (C), Guanine (G), Uracil (U)/Thymine (T) for the genetic alphabet.
Although much is known about the structure and composition of DNA the reason behind
nature's particular choice of nucleotide alphabet over the many conceivable alternatives is not self-evident. Most studies have pursued physicochemical aspects of the problem while informatics aspects have been largely neglected, although they have been recently shown to play a fundamental role.
Author: Ní Chaoimh, Lavina Dewdney
Advisor:
Mac Dónaill, DónallQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). School of ChemistryNote:
TARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ieType of material:
thesisAvailability:
Full text availableKeywords:
Chemistry, Ph.D., Ph.D. Trinity College Dublin.Metadata
Show full item recordLicences: