Browsing by Subject "Ph.D. Trinity College Dublin."
Now showing items 1-20 of 648
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A comparative genomics analysis of the vertebrate immune system : genes, pathways and evolution
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2009)All species possess a selection-honed collection of genes whose products function in unison to form a barricade to invading pathogens. The exponential increase in publicly available sequence data has allowed the application ... -
A computational exploration of a possible alternative to nucleotides as the basis of a genetic alphabet
(Trinity College (Dublin, Ireland). School of Chemistry, 2012)One of the most fundamental questions in molecular biology is why nature has chosen Adenine (A), Cytosine (C), Guanine (G), Uracil (U)/Thymine (T) for the genetic alphabet. Although much is known about the structure and ... -
A continuous flow arsenic removal system using solar oxidation
(Trinity College (Dublin, Ireland). Department of Civil, Structural and Environmental Engineering, 2012)It is estimated that over 100 million people worldwide are drinking water contaminated with arsenic. The World Health Organisation (WHO) set the maximum contaminant level for arsenic at 10μg/l in 1996 as it is not only ... -
A dynamic study of the characteristics, predictive power and profitable opportunities underlying takeover prediction models : evidence from the UK and the USA
(Trinity College (Dublin, Ireland). Trinity Business School, 2010)Takeover prediction models can be defined as a cross-sectional regression using a firms corporate accounting information in order to measure its likelihood of becoming an acquisition target. Given the theoretical and ... -
A functional genomics approach to study plant reproductive development
(Trinity College (Dublin, Ireland). Department of Genetics, 2012)A fundamental question in developmental biology is how differentiated cell types and organs are formed from undifferentiated precursor cells. The establishment of the body plan of an organism is ultimately defined by its ... -
A generalized method for quantification of cognitive radio benefits within wireless systems
(Trinity College (Dublin, Ireland). Department of Electronic & Electrical Engineering, 2009)For most of the history of wireless communications, the primary enabler of enhanced radio communications capability and utility has been continual improvement in the implementing technology and the corresponding ability ... -
A geometrical approach to spike train noise
(Trinity College (Dublin, Ireland). School of Mathematics, 2012)Mathematically, spike trains are elusive processes. They encode information, although how this information is contained in a spike train is still not clear. Same-stimulus spike trains display structural similarities, yet ... -
A lesson in presents : social change in the writing of Brendan Kennelly, 1980-2000
(Trinity College (Dublin, Ireland). School of English, 2012)This thesis explores the relationship between form in the writing of Irish poet Brendan Kennelly and social change in Ireland between 1980 and 2000. Using the ideas of postmodern theorists including Jean-Frangois Lyotard, ... -
A longitudinal study of portfolio use to assess the competence of undergraduate student nurses
(Trinity College (Dublin, Ireland). School of Education, 2012)With the advent of the new BSc programmes, An Bord Altranais, the regulatory body for professional nursing would no longer host what was known as the 'state final examinations'. Until this time, decisions on whether or not ... -
A new approach to driving cycle development and its applications
(Trinity College (Dublin, Ireland). Department of Civil, Structural and Environmental Engineering, 2013)Driving cycles describe the general driving pattern of a vehicle in a road network, and are usually represented by speed-time profiles of equal spacing. They are used to approximate and represent driving conditions as an ... -
A non-perturbative study of the renormalisation of action parameters in anisotropic lattice QCD with applications to finite temperature QCD
(Trinity College (Dublin, Ireland). School of Mathematics, 2009)The advantages of using anisotropic lattices, instead of the more usual isotropic lattices, in QCD simulations are well estabhshed. Anisotropic lattices can be used to increase signal resolution and allow computational ... -
A perfection of means and confusion of aims : finding the essence of autonomy in assisted death laws
(Trinity College (Dublin, Ireland). School of Law, 2012)This thesis was developed through standard library-based research methods as well as legal research conducted via the internet and electronic databases including LexisNexis, QuickLaw, Westlaw and HeinOnline as well as the ... -
A Power to Bite upon the Imagination' : ecclesiastical, ideological, and cultural controversies in the domestic novels of Charlotte Mary Yonge
(Trinity College (Dublin, Ireland). Centre for Gender and Women's Studies, 2012)This dissertation investigates and interprets the ways in which Charlotte Mary Yonge (1823-1901), one of the most popular and prolific authors of the nineteenth century, was read, represented, reviewed, and remembered. It ... -
A role for type 111 interferons in the natural killer cell immune response to virus
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2012)Natural Killer (NK) cells are fundamental effector cells of the innate immune system that function to eliminate virally infected and transformed cells. One key way in which they do this is through the production of cytokines, ... -
A semiclassical approach to quantum Brownian motion in Wigner's phase space
(Trinity College (Dublin, Ireland). Department of Electronic & Electrical Engineering, 2010)In this thesis, the recent semiclassical approach to quantum Brownian motion of Coffey et al. [Phys. Chem. Chem. Phys. 9, 3361 (2007)] is studied in detail. This approach is based on a semiclassical extension of Wigner's ... -
A social history of the Irish music industry, 1910 - 1985
(Trinity College (Dublin, Ireland). Department of Sociology, 2015)This thesis re-inserts a number of key behind-the-scenes individuals and factors into the history of the Irish music industry, placing the commercial and artistic achievements of Ireland's popular music artists in their ... -
A structural study of ALgE, transporter of alginate from Pseudomonas aeruginosa PAOI
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2013)Pseudomonas aeruginosa is an opportunistic human pathogen that causes serious diseases in humans with immune system deficiencies, such as cystic fibrosis, wound infections, urinary tract infections, and blood stream ... -
A study of the glycosylphosphatidylinositol phospholipase C in Trypanosoma brucei
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2013)Trypanosoma brucei represents a clade of flagellated parasites that cause human and animal trypanosomiases in sub-Saharan Africa. The glycosylphosphatidylinositol phospholipase C (GPI-PLC) is an endogenous enzyme that has ... -
A study of the management and treatment of substance mususe problems in a Regional Health Board in Ireland
(Trinity College (Dublin, Ireland). School of Social Work and Social Policy, 2009)This study presents the findings of a research project conducted within a Regional Health Board in Ireland and aimed at evaluating the way in which the public health service responds to alcohol-related problems; the study ... -
A study of the regulation of aminoacyl tRNA synthetase gene expression in Bacillus by T-box regulatory elements
(Trinity College (Dublin, Ireland). School of Genetics and Microbiology, 2010)The T-box antitermination mechanism is commonly used for the regulation of aminoacyl tRNA synthetase gene expression in Gram positive bacteria. However, expression of lysyl tRNA synthetases is rarely controlled in this ...