Therapeutic approaches to halting photoreceptor cell death in the retina
Citation:
Gearóid Patrick Tuohy, 'Therapeutic approaches to halting photoreceptor cell death in the retina', [thesis], Trinity College (Dublin, Ireland). School of Genetics and Microbiology, 2001, pp 260Download Item:
Tuohy TCD THESIS 6441 Therapeutic approaches.pdf (PDF) 234.7Mb
Abstract:
Retinitis pigmentosa (RP) is a group of hereditary retinopathies affecting approximately
1 in 3500 people in the developed world. The disorders are characterised by the early
onset of night blindness followed by a progressive loss of the visual field. The primary
defect underlying RP affects the rod photoreceptor cell and subsequently , mostly
unknown molecular and cellular mechanisms trigger the apoptotic degeneration of
both rod and cone photoreceptors. A further major characteristic of this group of
disorders is the genetic and clinical heterogeneity which has complicated the
developments of therapeutic strategies aimed at slowing or halting photoreceptor cell
death.
Author: Tuohy, Gearóid Patrick
Qualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). School of Genetics and MicrobiologyNote:
TARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.iePrint thesis water damaged as a result of the Berkeley Library Podium flood 25/10/2011
Type of material:
thesisAvailability:
Full text availableKeywords:
Genetics, Ph.D., Ph.D. Trinity College DublinLicences: