Browsing Microbiology by Subject "Genes & Society"
Now showing items 1-20 of 69
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Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus
(2014)Staphylococcus aureus is an important opportunistic pathogen and persistently colonizes about 20% of the human population. Its surface is 'decorated' with proteins that are covalently anchored to the cell wall peptidoglycan. ... -
Bacterial DNA topology and infectious disease
(2009)he gram-negative bacterium Escherichia coli and its close relative Salmonella enterica have made important contributions historically to our understanding of how bacteria control DNA supercoiling and of how supercoiling ... -
Bacterial regulon evolution: distinct responses and roles for the identical OmpR proteins of Salmonella Typhimurium and Escherichia coli in the acid stress response
(2014)The evolution of new gene networks is a primary source of genetic innovation that allows bacteria to explore and exploit new niches, including pathogenic interactions with host organisms. For example, the archetypal DNA ... -
Broad scale redistribution of mRNA abundance and transcriptional machinery in response to growth rate in Salmonella enterica serovar Typhimurium
(2017)We have investigated the connection between the four-dimensional architecture of the bacterial nucleoid and the organism's global gene expression programme. By localizing the transcription machinery and the transcriptional ... -
Clumping factor A interaction with complement factor I increases C3b cleavage on the bacterial surface of Staphylococcus aureus, and decreases complement-mediated phagocytosis
(2010)The human complement system is important in the immunological control of Staphylococcus aureus infection. We showed previously that S. aureus surface protein clumping factor A (ClfA), when expressed in recombinant form, ... -
Co-operative roles for DNA supercoiling and nucleoid-associated proteins in the regulation of bacterial transcription
(2013)DNA supercoiling and NAPs (nucleoid-associated proteins) contribute to the regulation of transcription of many bacterial genes. The horizontally acquired SPI (Salmonella pathogenicity island) genes respond positively to ... -
The complex and dynamic genomes of industrial yeasts
(2009)The Saccharomyces sensu stricto genus contains many species that are industrially important for fermentation of wines, beers and ales. The molecular characterization of the genomes of yeasts involved in these processes ... -
Control of virulence gene transcription by indirect readout in Vibrio cholerae and Salmonella enterica serovar Typhimurium
(2017)Indirect readout mechanisms of transcription control rely on the recognition of DNA shape by transcription factors (TFs). TFs may also employ a direct readout mechanism that involves the reading of the base sequence in the ... -
Deletion of the nuclear exosome component RRP6 leads to continued accumulation of the histone mRNA HTB1 in S-phase of the cell cycle in Saccharomyces cerevisiae.
(2007)The nuclear exosome, a macromolecular complex of 3 ’ to 5 ’ exonucleases, is required for the post- transcriptional processing of a variety of RNAs including rRNAs and snoRNAs. Additionally, this complex forms part ... -
DNA supercoiling and the Lrp protein determine the directionality of fim switch DNA inversion in Escherichia coli K-12
(2006)Site-specific recombinases of the integrase family usually require cofactors to impart directionality in the recombination reactions that they catalyze. The FimB integrase inverts the Escherichia coli fim switch (fimS) in ... -
DNA supercoiling and transcription: a two-way street
(2019)Background : The processes of DNA supercoiling and transcription are interdependent because the movement of a transcription elongation complex simultaneously induces under- and over winding of the DNA duplex and because ... -
Ecological dependencies and the illusion of cooperation in microbial communities
(2024)Ecological dependencies - where organisms rely on other organisms for survival - are a ubiquitous feature of life on earth. Multicellular hosts rely on symbionts to provide essential vitamins and amino acids. Legume plants ... -
The effect of mobile element IS10 on experimental regulatory evolution in Escherichia coli
(2010)Mobile genetic elements are widespread in bacteria, where they cause several kinds of mutations. Although their effects are on the whole negative, rare beneficial mutations caused by insertion sequence elements are frequently ... -
Engineering Saccharomyces pastorianus for the co-utilisation of xylose and cellulose from biomass.
(2015)Background Lignocellulosic biomass is a viable source of renewable energy for bioethanol production. For the efficient conversion of biomass into bioethanol, it is essential that sugars from both the cellulose and ...