Browsing Biochemistry (Scholarly Publications) by Subject "Genes & Society"
Now showing items 1-15 of 15
-
Absence of mitochondrial uncoupling protein 3: Effect on thymus and spleen in the fed and fasted mice
(2011)Mitochondrial uncoupling protein 3 (UCP3) is consituitively expressed in mitochondria from thymus and spleen of mice, and confocal microscopy has been used to visualize UCP3 in situ in mouse thymocytes. UCP3 is present ... -
Congruence of tissue expression profiles from Gene Expression Atlas, SAGEmap and TissueInfo databases.
(2003)Background: Extracting biological knowledge from large amounts of gene expression information deposited in public databases is a major challenge of the postgenomic era. Additional insights may be derived by data integration ... -
Detecting microRNA activity from gene expression data.
(2010)ABSTRACT: BACKGROUND: MicroRNAs (miRNAs) are non-coding RNAs that regulate gene expression by binding to the messenger RNA (mRNA) of protein coding genes. They control gene expression by either inhibiting translation or ... -
Effect of dietary restriction and subsequent realimentation on hepatic oxidative phosphorylation in cattle
(2021)Compensatory growth (CG) is a naturally accelerated growth which occurs upon realimentation, following a prior period of dietary restriction. The process is harnessed worldwide as a management practice to reduce feed costs ... -
Genome-wide transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis reveals suppression of host immune genes
(2011)Background: Mycobacterium bovis is the causative agent of bovine tuberculosis (BTB), a pathological infection with significant economic impact. Recent studies have highlighted the role of functional genomics to better ... -
In vitro Blood Cell Responsiveness to IFN-alpha Predicts Clinical Response Independently of IL28B in Hepatitis C Virus Genotype 1 Infected Patients.
(2014)BACKGROUND: Treatment with interferon-alpha (IFN-α) and ribavirin successfully clears hepatitis C virus (HCV) infection in 50% of patients infected with genotype 1. Addition of NS3-4A protease inhibitors (PIs) increases ... -
Queuosine formation in eukaryotic tRNA occurs via a mitochondrial localized heteromeric transglycoslase.
(2009)tRNA guanine transglycosylase (TGT) enzymes are responsible for the formation of queuosine in the anticodon loop (position 34) of tRNAAsp, tRNAAsn, tRNAHis, and tRNATyr; an almost universal event in eubacterial and eukaryotic ... -
Residual feed intake phenotype and gender affect the expression of key genes of the lipogenesis pathway in adipose tissue of beef cattle
(2018)Background: Feed accounts for up to 75% of costs in beef production systems, thus any improvement in feed efficiency (FE) will benefit the profitability of this enterprise. Residual feed intake (RFI) is a measure of FE ... -
Ribavirin Enhances IFN-α Signalling and MxA Expression: A Novel Immune Modulation Mechanism during Treatment of HCV
(2011)The nucleoside analogue Ribavirin significantly increases patient response to IFN-? treatment of HCV, by directly inhibiting viral replication. Recent studies indicate that Ribavirin also regulates immunity and we propose ... -
The "speed gene" effect of myostatin arises in Thoroughbred horses due to a promoter proximal SINE insertion
(2018)Thoroughbred horses are finely-tuned athletes with a high aerobic capacity relative to skeletal muscle mass, attributable to centuries of genetic selection for speed and stamina. Polymorphisms in the myostatin gene (MSTN), ... -
Toll-like receptor 4 (TLR4) down-regulates microRNA-107 increasing macrophage adhesion via cyclin-dependent kinase 6
(2011)Toll-like receptors (TLRs) modulate the expression of multiple microRNAs (miRNAs). Here we report the down-regulation of miR-107 by TLR4 in multiple cell types. The miR-107 sequence occurs in an intron within the sequence ...