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  Mitochondrial localization of SESN2 

  Budanov, Andrei; Kovaleva, Irina E.; Tokarchuk, Artem V.; Zheltukhin, Andrei O.; Dalina, Alexandra A.; Safronov, Grigoriy G.; Evstafieva, Alexandra G.; Lyamzaev, Konstantin G.; Chumakov, Peter M. (2020)

  SESN2 is a member of the evolutionarily conserved sestrin protein family found in most of the Metazoa species. The SESN2 gene is transcriptionally activated by many stress factors, including metabolic derangements, reactive ...
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  Partial inhibition of complex I activity increases Ca2+-independent glutamate release rates from synaptosomes 

  DAVEY, GAVIN; Kilbride, Seán M.; Telford, Jayne E.; Tipton, Keith F. (2008)

  Mitochondria have been implicated in the pathogenesis of several neurodegenerative disorders and, in particular, complex I (NADH:ubiquinone oxidoreductase, EC 1.6.5.3) activity has been shown to be partially reduced in ...
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  Autophagy in the immune response to tuberculosis: clinical perspectives 

  KEANE, JOSEPH; HARRIS, JAMES; LAVELLE, EDWARD; NI CHEALLAIGH, CLIONA; Hope, J.C. (2011)

  A growing body of evidence points to autophagy as an essential component in the immune response to tuberculosis. Autophagy is a direct mechanism of killing intracellular Mycobacterium tuberculosis and also acts as a modulator ...
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  Metabolic reprogramming during the Trypanosoma brucei life cycle 

  NOLAN, DEREK; Smith, Terry K.; Bringaud, Frédéric; Figueiredo, Luisa M. (2017)

  Cellular metabolic activity is a highly complex, dynamic, regulated process that is influenced by numerous factors, including extracellular environmental signals, nutrient availability and the physiological and developmental ...
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  Retroviral reporter systems for the assessment of activity of stress-induced signal transduction pathways controlled by p53, HIF-1 and HSF-1 transcription factors 

  Budanov, Andrei; Razorenova, O.V.; Agapova, L.S.; Ivanov, A.V.; Strunina, S.M.; Chumakov, P.M. (2005)

  The tumor suppressor p53, hypoxia-inducible factor 1 (HIF-1), and heat-shock factor 1 (HSF-1) are the key transcription factors involved in the stress response to damage of the genetic material, hypoxia, or heat shock, ...

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