RSS 1.0Biochemistry (Scholarly Publications)
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Guardians of the Cell: Effector-Triggered Immunity Steers Mammalian Immune Defense
(2019)The mammalian innate immune system deals with invading pathogens and stress by activating pattern-recognition receptors (PRRs) in the host. Initially proposed to be triggered by the discrimination of defined molecular ... -
Bioenergetics of acquired cisplatin resistant H1299 non-small cell lung cancer and P31 mesothelioma cells
(Impact Journals, 2017)Acquired cisplatin resistance is a common feature of tumours following cancer treatment with cisplatin and also of non-small cell lung cancer (H1299) and mesothelioma (P31) cell lines exposed to cisplatin. To elucidate the ... -
The "speed gene" effect of myostatin arises in Thoroughbred horses due to a promoter proximal SINE insertion
(2018)Thoroughbred horses are finely-tuned athletes with a high aerobic capacity relative to skeletal muscle mass, attributable to centuries of genetic selection for speed and stamina. Polymorphisms in the myostatin gene (MSTN), ... -
Caspase-11 Mediated Cell Death Contributes to the Pathogenesis of Imiquimod-Induced Psoriasis
(2019)Inflammasomes are multiprotein complexes that respond to infection or injury to activate inflammation. Inflammatory caspases, caspase-1, 4 and 5 in humans, and their murine orthologues caspase-1 and 11 are crucial components ... -
Residual feed intake phenotype and gender affect the expression of key genes of the lipogenesis pathway in adipose tissue of beef cattle
(2018)Background: Feed accounts for up to 75% of costs in beef production systems, thus any improvement in feed efficiency (FE) will benefit the profitability of this enterprise. Residual feed intake (RFI) is a measure of FE ...
