Browsing Public Health & Primary Care (Scholarly Publications) by Author "ZGAGA, LINA"
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Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.
ZGAGA, LINA (2014)BACKGROUND: Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether this association is causal is unknown. We used a mendelian randomisation ... -
DNA mismatch repair gene MSH6 implicated in determining age at natural menopause.
ZGAGA, LINA (2014)The length of female reproductive lifespan is associated with multiple adverse outcomes, including breast cancer, cardiovascular disease and infertility. The biological processes that govern the timing of the beginning and ... -
Genome-wide association analysis identifies six new loci associated with forced vital capacity.
ZGAGA, LINA; LOPEZ, LORNA (2014)Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung volume and is used to diagnose and monitor lung diseases. We performed genome-wide association study meta-analysis of FVC in 52,253 ... -
Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory.
ZGAGA, LINA (2014)Mega- or meta-analytic studies (e.g. genome-wide association studies) are increasingly used in behavior genetics. An issue in such studies is that phenotypes are often measured by different instruments across study cohorts, ... -
Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.
ZGAGA, LINA (2014)To identify common variants influencing colorectal cancer (CRC) risk, we performed a meta-analysis of five genome-wide association studies, comprising 5626 cases and 7817 controls of European descent. We conducted replication ... -
Plasma Vitamin D Concentration Influences Survival Outcome After a Diagnosis of Colorectal Cancer
ZGAGA, LINA (2014)PURPOSE: We investigated whether the plasma level of 25-hydroxyvitamin D (25-OHD) after a diagnosis of colorectal cancer (CRC) influences survival outcome. PATIENTS AND METHODS: We prospectively studied 1,598 patients ... -
SMAD7 variant rs4939827 is associated with colorectal cancer risk in Croatian population.
ZGAGA, LINA (2013)Background Twenty common genetic variants have been associated with risk of developing colorectal cancer (CRC) in genome wide association studies to date. Since large differences between populations exist, generalisability ...