New families of minor groove binders : synthesis, biophysical and biochemical evaluation and their role in apoptosis
Citation:
Amila Kahvedžić, 'New families of minor groove binders : synthesis, biophysical and biochemical evaluation and their role in apoptosis', [thesis], Trinity College (Dublin, Ireland). School of Chemistry, 2011, pp 353Download Item:
Abstract:
There is an active field in the design and synthesis of DNA targeting molecules as
potential anticancer agents. Although a number of successful drug treatments against a variety of cancers are in clinical use, many of these have little sequence specificity and as a result exhibit high toxic side effects on normal tissues. Consequently, it is essential that these existing agents are optimised and new more improved agents be designed.
Author: Kahvedžić, Amila
Advisor:
Rozas, IsobelQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). School of ChemistryNote:
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Full text availableKeywords:
Chemistry, Ph.D., Ph.D. Trinity College Dublin.Metadata
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