Biological investigations of novel 1,8-naphthalimide compounds and the design and synthesis of pyridine based polyamides
Citation:
Daniel Ómar Frímannsson, 'Biological investigations of novel 1,8-naphthalimide compounds and the design and synthesis of pyridine based polyamides', [thesis], Trinity College (Dublin, Ireland). School of Chemistry, 2009, pp 236Download Item:
Abstract:
This thesis entitled "Biological Investigations of Novel 1,8-Naphthalimide
Compounds and the Design and Synthesis of Pyridine Polyamides" is divided into six
chapters. Chapter 1, the introduction focuses on the basic cellular mechanisms, such as
growth and programmed cell death and their connection to cancer. Furthermore, the
different means of inhibiting the growth of cancer cells is discussed, followed by examples
of organic compounds that have been synthesised with that it mind. Special focus will be
given to the genetic material, DNA and agents that have been designed to interact with it.
Author: Frímannsson, Daniel Ómar
Advisor:
Gunnlaughsson, ThorfinnurQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). School of ChemistryNote:
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Full text availableKeywords:
Chemistry, Ph.D., Ph.D. Trinity College Dublin.Licences: