Browsing Genetics by Author "SHERIDAN, CLARE"

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    • Mitochondrial fission/fusion dynamics and apoptosis 

      MARTIN, SEAMUS; SHERIDAN, CLARE (2010)
      Mitochondria play an important role in the progression of apoptosis through the release of pro-apoptotic factors, such as cytochrome c, from the mitochondrial intermembrane space. During this process, mitochondrial networks ...

    • Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases 

      LAVELLE, EDWARD; MARTIN, SEAMUS JOSEPH; LUTHI, ALEXANDER; SHERIDAN, CLARE (2009)
      Interleukin-33 (IL-33) is a member of the IL-1 family and is involved in polarization of T cells toward a T helper 2 (Th2) cell phenotype. IL-33 is thought to be activated via caspase-1-dependent proteolysis, similar to ...