Browsing Trinity College Dublin Theses & Dissertations by Subject "Rab GTPases"
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Structural aspects of the regulation of Parkinson's Disease-associated LRRK2 Kinase by Rab GTPases
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2019)The Rab family of small GTPases are the premier organisers of endocytic and secretory pathways in cells. They behave as molecular 'on/off' switches and in their active GTP-bound state recruit soluble effector proteins to ...