Browsing Trinity College Dublin Theses & Dissertations by Subject "Haematology, M.D."
Now showing items 1-4 of 4
-
Defining inherited haematological disease within the Irish traveller population
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Haematology, 2006)The Traveller Community in Ireland constitutes a minority of nomadic or semi-nomadic people, sharing a common Irish ancestry. The Traveller Health Study showed that in 1987, Travellers were only reaching the life expectancy ... -
Prostate cancer progression to androgen independence - do changes in the androgen receptor CAG repeat number play a role?
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Haematology, 2007)Prostate cancer is the commonest non-cutaneous male malignancy and is the second commonest cause of cancer-related deaths in many Western countries. Approximately half of all men diagnosed with prostate cancer will have ... -
Role of membrane lipids and plasma lipoproteins in the regulation of activated protein C function
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Haematology, 2013)Activated protein C (APC) is an important anticoagulant factor that serves to downregulate thrombin generation. APC also has several cytoprotective properties, including anti-apoptotic and endothelial barrier stabilizing ... -
Variation in DNA repair genes XRCC3, XRCC4, and XRCC5 and susceptibility ot myeloma
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Haematology, 2010)Cytogenetic analysis in myeloma reveals marked chromosomal instability. Both widespread genomic alterations and evidence of aberrant class switch recombination, the physiological process that regulates maturation of the ...