Browsing Trinity College Dublin Theses & Dissertations by Sponsor "H2020-MSCA-ITN-2019 (Grant No 813343)"
Now showing items 1-1 of 1
-
Mechanisms of gasdermin pore formation in response to viral sensing in human respiratory epithelial cells
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)A key component of the innate immune response to infection or cellular stress is the activation of inflammasomes which leads to gasdermin (GSDM) pore formation, interleukin-1β (IL-1β) release and lytic cell death. GSDMs ...