Browsing Trinity College Dublin Theses & Dissertations by Sponsor "Enterprise Ireland"
Now showing items 1-8 of 8
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3D Bioprinted Cartilaginous Templates as Developmentally Inspired Implants for Large Bone Defect Regeneration
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)Whilst bone possesses an inherent capacity for regeneration, defects above a critical size cannot heal on their own. Damaged or diseased bone can be treated using autografts or a range of different bone grafting biomaterials, ... -
A Bridgman Furnace Front Tracking Model
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2015)The Bridgman furnace is widely used in industry and research, mainly because it provides a means to directionally solidify materials in a controlled manner, so that the resulting microstructure, and hence material properties, ... -
CRISPR Gene Editing Approaches in the Study of Allergy and Infertility
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2019) -
Development of audio-based signal processing methods to objectively assess patient adherence in respiratory medicine
(Trinity College Dublin. School of Engineering. Discipline of Electronic & Elect. Engineering, 2018)Over four million people die every year from chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). There is no cure currently available for these diseases; however, they may be ... -
Exploring Membrane Transporters in Lung Epithelial Cells: Drug-Transporter Interaction Analyses in Different In Vitro Models
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)Over the last decade, the incidence of lung-related diseases such as asthma and chronic obstructive pulmonary disease and their associated morbidity have continuously risen. A heterogeneity in treatment response to commonly ... -
Optimal Real-Time Predictive Control for Maximising the Power-Take-Off Efficiency of the WaveRAM Wave Energy Converter
(Trinity College Dublin. School of Engineering. Disc of Civil Structural & Environmental Eng, 2018)The aim of this thesis is to develop a control strategy for optimising the power-take-off (PTO) efficiency of the newly developed WaveRAM (WRAM) wave energy converter. The three main research streams established to satisfy ... -
Platelet-cancer Cell Interactions induce PAI-1 Expression in an Ovarian Cancer Cell Line Model: Implications for the Metastasis of Epithelial Ovarian Cancer
(Trinity College Dublin. School of Medicine. Discipline of Histopathology, 2021)This thesis encompasses an investigation into the function of plasminogen activator inhibitor 1 (PAI-1) - a serine protease inhibitor integral to coagulation and fibrinolysis that has been identified as both a key factor ... -
Towards a formal method for distributed object-oriented systems
(Trinity College (Dublin, Ireland). School of Computer Science & Statistics, 2004)We present two components of a special purpose formal method intended to support the modelling and development of distributed object-oriented systems. The first component is a language, called Oompa, in which designs for ...