Browsing Trinity College Dublin Theses & Dissertations by Author "Caboni, Laura"
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Thinking outside the NR box : advancing novel non ligand binding pocket antagonists for the human androgen receptor
Caboni, Laura (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2012)Current treatment of prostate cancer (PCa) typically involves administration of 'classical' antiandrogens, competitive inhibitors of natural androgen receptor (AR) ligands, dihydrotestosterone (DHT) and testosterone (tes), ...