Search
Now showing items 1-10 of 31
Intermolecular interactions between salmon calcitonin, hyaluronate, and chitosan and their impact on the process of formation and properties of peptide-loaded nanoparticles.
(2014)
The principal aim of this work was to study the formulation of a ternary complex comprising salmon calcitonin (sCT), hyaluronate (HA), and chitosan (CS) in a nanoparticle (NP) format. As interactions between the constituents ...
The impact of the degree of intimate mixing on the compaction properties of materials produced by crystallo-co-spray drying
(2020)
Direct compression remains one of the most favourable methods available to produce tablet compacts due to its simplicity, efficiency and cost effectiveness however, the technique still remains unsuitable for the majority ...
In vivo assessment of parenteral formulations of oligo(3-hydroxybutyric acid) conjugates with the model compound ibuprofen
(2010)
Polymer-drug conjugates have gained significant attention as pro-drugs releasing an active substance as a result of enzymatic hydrolysis in physiological environment. In this study, a conjugate of 3-hydroxybutyric acid ...
Impact of substrate properties on the formation of spherulitic films: a case study of salbutamol sulfate
(2016)
Spherulitic assemblies have applications as carriers for drug delivery and as targeting vectors. Presently, the driving force behind the formation of spherulites comprising small drug molecules is not fully understood. ...
In Situ Monitoring of Nanoparticle Formation: Antisolvent Precipitation of Azole Anti-fungal Drugs.
(2018)
In this work we report the effect of stabilizer choice and concentration on nanoparticle (NP) stability over time. Three different BCS class II active pharmaceutical ingredient (APIs): itraconazole (ITR), ketoconazole ...