Browsing School of Pharmacy and Pharmaceutical Sciences by Sponsor "European Union (EU)"
Now showing items 1-9 of 9
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Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles.
(2019)There is an increasing interest in exploring clinically relevant information that is present in body fluids, and extracellular vesicles (EVs) are intrinsic components of body fluids (“liquid biopsies”). In this report, we ... -
Identification and Pharmaceutical Characterization of a New Itraconazole Terephthalic Acid Cocrystal
(2020)The crystallization of poorly soluble drug molecules with an excipient into new solid phases called cocrystals has gained a considerable popularity in the pharmaceutical field. In this work, the cocrystal approach was ... -
Mesenchymal Stem Cell Derived Extracellular Vesicles for Tissue Engineering and Regenerative Medicine Applications
(2020)Mesenchymal stem cells (MSCs) are being extensively investigated for their potential in tissue engineering and regenerative medicine. However, recent evidence suggests that the beneficial effects of MSCs may be manifest ... -
miR-134 in extracellular vesicles reduces triple-negative breast cancer aggression and increases drug sensitivity
(2015)Exosomes (EVs) have relevance in cell-to-cell communication carrying pro- tumorigenic factors that participate in oncogenesis and drug resistance and are proposed to have potential as self-delivery systems. Advancing ... -
Physicochemical Characterization of a Co-Amorphous Atorvastatin-Irbesartan System with a Potential Application in Fixed-Dose Combination Therapy
(2021)The aim of this study was to characterize a 1:1 molar ratio of a pharmacologically relevant co-amorphous atorvastatin-irbesartan (ATR-IRB) system obtained by quench cooling of the crystalline ATR/IRB physical mixture for ... -
Recommendations for In Vitro and In Vivo Testing of Magnetic Nanoparticle Hyperthermia Combined with Radiation Therapy.
(2018)Magnetic nanoparticle (MNP)-mediated hyperthermia (MH) coupled with radiation therapy (RT) is a novel approach that has the potential to overcome various practical difficulties encountered in cancer treatment. In this work, ... -
Stability of salmon calcitonin against trypsin, chymotrypsin and neutrophil elastase in human lung epithelial cells
(2010)At least three enzymes (i. e., trypsin, chymotrypsin and neutrophil elastase) are responsible for the degradation of salmon calcitonin (sCT) in the human body. Here, we investigated how these proteinases affect drug ...