Browsing Microbiology by Author "Bond, Ursula"
Now showing items 1-16 of 16
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Accelerated Evolution of Lager Yeast Strains for Improved Flavour Profiles
De La Cerda García-Caro, Roberto (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Microbiology, 2022)S. pastorianus is an interspecific hybrid resulting from natural hybridization between S. cerevisiae and S. eubayanus. These two species belong to the Saccharomyces genus, a genus that encompasses different species related ... -
Analysis of the genomic organisation and gene expression of brewery strains of yeast
Usher, Jane (Trinity College (Dublin, Ireland). Department of Microbiology, 2008)The genomes of lager yeast arose from the fusion of two yeast strains most closely resembling Saccharomyces cerevisiae and Saccharomyces bayanus. The resultant strains have subsequently undergone genome duplications ... -
Aneuploidy influences the gene expression profiles in Saccharomyces pastorianus group I and II strains during fermentation
Bond, Ursula; Hokamp, Karsten (2022)The lager yeasts, Saccharomyces pastorianus, are hybrids of Saccharomyces cerevisiae and Saccharomyces eubayanus and are divided into two broad groups, Group I and II. The two groups evolved from at least one common ... -
Antimicrobial peptide preventing beer spoilage
Kavanagh, Joanne Denise (Trinity College (Dublin, Ireland). Department of Microbiology, 2012)Beer spoilage micro-organisms (BSMs) are a common threat to Master Brewers worldwide. Numerous studies have been carried out to date to overcome this problem, yet the most common preventative measure is the addition of ... -
Biogenesis of histone mRNAs in the yeast Saccharomyces cerevisiae
Canavan, Ruth Alice (Trinity College (Dublin, Ireland). Department of Microbiology, 2007)The typical eukaryotic human diploid cell contains 3.2x10 9 base pairs of deoxyribonucleic acid (DNA) which, if presented in an extended form, would measure 1.2m in length. The large amount of DNA is tightly wrapped and ... -
Biomass to biofuel : the engineering of Saccharomyces species for the co-fermentation of cellulose and xylose
Kricka, William Laurence (Trinity College (Dublin, Ireland). Department of Microbiology, 2015)Lignocellulose represents one of the most abundant biomass sources in the world. Its renewable and abundant nature makes it a prime target for use in bioethanol production. The efficient conversion of lignocellulosic biomass ... -
Biomass to biofuel : towards the bioengineering of Saccharomyces species for cellulose degradation
Fitzpatrick, James (Trinity College (Dublin, Ireland). Department of Microbiology, 2011)Cellulose is the most abundant polysaccharide on earth and therefore represents a major reservoir of sugar that could be potentially converted to alcohol and used as a fuel source. The filamentous fungus Trichoderma reesei ... -
Characterization of peptide mimics to antigens chaperoned by Hsp70 in MDA-MB-231 breast tumour cells
Arnaiz Villanueva, Blanca Esther (Trinity College (Dublin, Ireland). Department of Microbiology, 2005)Tumour-derived heat shock protein (Hsp) preparations have been shown to elicit anti-tumour immune responses in both mice and man. Analysis of Hsp preparations from tumour cells revealed that the immuno-protective property ... -
Fermentation innovation through complex hybridization of wild and domesticated yeasts
Bond, Ursula (2019)The most common fermented beverage, lager beer, is produced by interspecies hybrids of the brewing yeast Saccharomyces cerevisiae and its wild relative S. eubayanus. Lager-brewing yeasts are not the only example of hybrid ... -
The hybrid genomes of Saccharomyces pastorianus-a current perspective
Bond, Ursula; Monerawela, Chandre (2018)Saccharomyces pastorianus is a recently evolved interspecies hybrid of Saccharomyces cerevisiae and Saccharomyces eubayanus used in the production of lager-type beers and has a long-standing history with the brewing industry. ... -
Identification of factors involved in 3' end processing and transcription termination of histone mRNAs
Beggs, Suzanne Martina (Trinity College (Dublin, Ireland). Department of Microbiology, 2011)The production of core histone mRNAs is tightly regulated during the cell cycle in all eukaryotic cells. Histone mRNAs accumulate during the S-phase and are subsequently degraded upon entry into G2-phase of the cell cycle. ... -
Packing a punch: Understanding how flavours are produced in lager fermentations
Bond, Ursula (2021)Beer is one of the most popular beverages in the world and it has an irreplaceable place in culture. Although invented later than ale, lager beers dominate the current market. Many factors relating to the appearance (colour, ... -
Population genomics of the pathogenic yeast Candida tropicalis identifies hybrid isolates in environmental samples
Bond, Ursula (2021)Candida tropicalis is a human pathogen that primarily infects the immunocompromised. Whereas the genome of one isolate, C. tropicalis MYA-3404, was originally sequenced in 2009, there have been no large-scale, multi-isolate ... -
The identification of novel peptides using phage display with the potential for use in breast cancer therapy
Siebke, Christina (Trinity College (Dublin, Ireland). Department of Microbiology, 2011)Breast cancer is a leading cause of cancer-related mortality in women. Current treatments for breast cancer include surgery, radiotherapy, chemotherapy and hormone therapy. The recent development of Herceptin has added a ... -
Transcriptional Profile of the Industrial Hybrid Saccharomyces pastorianus Reveals Temperature-Dependent Allele Expression Bias and Preferential Orthologous Protein Assemblies
Bond, Ursula (2021)Saccharomyces pastorianus is a natural yeast evolved from different hybridization events between the mesophilic S. cerevisiae and the cold-tolerant S. eubayanus. This complex aneuploid hybrid carries multiple copies of the ...