Browsing Medical Gerontology by Title
Now showing items 208-227 of 373
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Insights into the clinical management of the syndrome of supine hypertension - orthostatic hypotension (SH-OH): The Irish Longitudinal Study on Ageing (TILDA)
(2013)BACKGROUND: Our previously proposed morphological classification of orthostatic hypotension (MOH) is an approach to the definition of three typical orthostatic hemodynamic patterns using non-invasive beat-to-beat ... -
Integrating genotypic data with transcriptomic and proteomic data.
(2002)Historically genotypic variation has been detected at the phenotypic level, at the metabolic level, and at the protein chemistry level. Advances in technology have allowed its direct visualisation at the level of DNA ... -
Intergenerational Occupational Mobility and Objective Physical Functioning in Midlife and Older
(2018)Objective: This study investigates the relationship between intergenerational occupational mobility and objective physical functioning in later life. Method: Data come from The Irish Longitudinal Study of Ageing (TILDA), ... -
Interrupting Bedtime to Reverse Frailty Levels in Acute Care: A Study Protocol for the Breaking Bad Rest Randomized Controlled Trial
(2023)Background Hospitalized older patients spend most of the waking hours in bed, even if they can walk independently. Excessive bedrest contributes to the development of frailty and worse hospital outcomes. We describe the ... -
Investigation of apraxia of speech and linguistic dysprosody following acute ischaemic hemispheral stroke
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2011)Apraxia of speech (AOS) is a disorder of motor speech programming. Affected patients typically have hesitant, groping speech with impaired prosody. Automatic speech is relatively well preserved compared to propositional ... -
Investigation of the role of sleep and physical activity risk for chronic disease prevalence in older Irish adults
(2022)Background: Chronic diseases are the leading cause of death worldwide. Many of these diseases have modifiable risk factors, including physical activity and sleep, and may be preventable. This study investigated independent ... -
Involving older people in co-designing a primary-care intervention to reverse frailty and build resilience
(2021)Background: An essential consideration in health research is to conduct research with members of the public rather than for them. Public and patient involvement (PPI) of older people in research can improve enrolment, ... -
Is orthostatic hypotension more common in individuals with atrial fibrillation? – Findings from The Irish Longitudinal Study on Ageing (TILDA)
(2017)Introduction: atrial fibrillation (AF) and orthostatic hypotension (OH) share common risk factors such as age, hypertension and cardiovascular (CV) disease. The autonomic nervous system (ANS) also plays a role in the ... -
Is phenotypical prefrailty all the same? A longitudinal investigation of two prefrailty subtypes in TILDA
(2019)Background: Fried's frailty phenotype is defined by five criteria: exhaustion, unexplained weight loss, weakness, slowness and low physical activity. Prefrailty (PF) meets one or two criteria. PF is of interest as a target ... -
Knowledge, skills and attitudes of doctors towards assessing cognition in older patients in the emergency department.
(2013)PURPOSE OF THE STUDY: Although cognitive impairment and delirium are highly prevalent in older patients who present to the emergency department, multiple studies have highlighted inadequate detection by doctors. This ... -
Lack Of Association Between Angiotensin-converting Enzyme (Ace) Genotype And Essential Hypertension In Peruvian Older People
(2020)Background: Epidemiological studies have shown an association between the ACE gene I / D polymorphism with arterial hypertension, specifically the DD genotype in different populations. The objective of this study is to ... -
Lack of association between angiotensin-converting enzyme genotype and muscle strength in Peruvian older people
(2020)Aging can be associated with decreasing muscle strength, and related factors are comorbidities, sex, physical activity, and possibly genetic factors. Among genetic factors the renin-angiotensin system is of interest, but ... -
The Lasting Legacy of Childhood Adversity for Disease Risk In Later Life
(2015)Objective: There has been an increased interest in the role of the childhood social environment in the etiology of adult diseases in recent years. The present study examines whether the experience of adversity during ... -
A linear regression-based machine learning pipeline for the discovery of clinically relevant correlates of gait speed reserve from multiple physiological systems
(2021)Frailty in older adults is characterized by reduced physiological reserve. Gait speed reserve (GSR: maximum minus usual gait speed) could help identify frailty and act as a proxy for physiological reserve. Utilizing data ... -
The Lived Experience of Frailty: Beyond Classification and Towards a Holistic Understanding of Health
(2024)Purpose: Frailty is characterised by decreased physiological reserves and vulnerability to stressors. Although scales such as the Fried’s Frailty Phenotype (FP), Frailty Index (FI), and Clinical Frailty Scale (CFS) are ...