Investigating the underlying mechanism of resistance to Ascaris infection
Citation:C. Dold and C.V. Holland, Investigating the underlying mechanism of resistance to Ascaris infection, Microbes and Infection, 13, 7, 2011, 624 - 631
Investigating the underlying mechanism of resistance to Ascaris infection.pdf (Accepted for publication (author's copy) - Peer Reviewed) 303.4Kb
The generative mechanism(s) of predisposition to Ascaris infection are currently unknown. While many factors play a role in interindividual infection intensity, much focus has been placed on the host's immunological response to infection and the underlying genetics. The present review describes the research conducted that has examined various immunological parameters and genetic factors that may play a role in resistance to ascariasis. We also discuss the contribution that animal models have made to our understanding of resistance to the parasitic roundworm and their role in possible future work.
Type of material:Journal Article
Series/Report no:Microbes and Infection
Availability:Full text available
Subject (TCD):Immunology, Inflammation & Infection