Search
Now showing items 1-10 of 16
Evidence that duplications of 22q11.2 protect against schizophrenia.
(2014)
A number of large, rare copy number variants (CNVs) are deleterious for neurodevelopmental disorders, but large, rare, protective CNVs have not been reported for such phenotypes. Here we show in a CNV analysis of 47 005 ...
Effects of MIR137 on fronto-amygdala functional connectivity.
(2014)
MIR137 is implicated in brain development and encodes a microRNA that regulates neuronal maturation and adult neurogenesis. Recently, a common genetic variant within MIR137 showed genome wide evidence of association with ...
No evidence that runs of homozygosity are associated with schizophrenia in an Irish genome-wide association dataset
(2014)
Runs of homozygosity (ROH), regions of the genome containing many consecutive homozygous SNPs, may represent two copies of a haplotype inherited from a common ancestor. A rare variant on this haplotype could thus be present ...
Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT).
(2014)
It has long been recognized that generalized deficits in cognitive ability represent a core component of schizophrenia (SCZ), evident before full illness onset and independent of medication. The possibility of genetic ...
Effects of a novel schizophrenia risk variant rs7914558 at CNNM2 on brain structure and attributional style.
(2014)
BACKGROUND:
A single nucleotide polymorphism (rs7914558) within the cyclin M2 (CNNM2) gene was recently identified as a common risk variant for schizophrenia. The mechanism by which CNNM2 confers risk is unknown.
AIMS:
To ...